Determining the Specificity of Cascade Binding, Interference, and Primed Adaptation <italic toggle="yes">In Vivo</italic> in the <italic toggle="yes">Escherichia coli</italic> Type I-E CRISPR-Cas System
ABSTRACT In clustered regularly interspaced short palindromic repeat (CRISPR)-Cas (CRISPR-associated) immunity systems, short CRISPR RNAs (crRNAs) are bound by Cas proteins, and these complexes target invading nucleic acid molecules for degradation in a process known as interference. In type I CRISP...
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| Main Authors: | , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2018
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| Subjects: | |
| Online Access: | https://doaj.org/article/4ca9f083d92b46669cff0a3137d48d4f |
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