Magnetic polymeric nanoassemblies for magnetic resonance imaging-combined cancer theranostics

Shenglong Gan,1,2,* Yisheng Lin,3,* Yancong Feng,1,2 Lingling Shui,1,2 Hao Li,1,2 Guofu Zhou1,2 1Guangdong Provincial Key Laboratory of Optical Information Materials and Technology and Institute of Electronic Paper Displays, South China Academy of Advanced Optoelectronics, South China Normal Univer...

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Autores principales:	Gan S, Lin Y, Feng Y, Shui L, Li H, Zhou G
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Polymer Nanoassembly Magnetic resonance imaging Cancer theranostics Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/4cb005dbb73346b8ac90826c5fd7ff1f
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spelling	oai:doaj.org-article:4cb005dbb73346b8ac90826c5fd7ff1f2021-12-02T07:16:27ZMagnetic polymeric nanoassemblies for magnetic resonance imaging-combined cancer theranostics1178-2013https://doaj.org/article/4cb005dbb73346b8ac90826c5fd7ff1f2018-07-01T00:00:00Zhttps://www.dovepress.com/magnetic-polymeric-nanoassemblies-for-magnetic-resonance-imaging-combi-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Shenglong Gan,1,2,* Yisheng Lin,3,* Yancong Feng,1,2 Lingling Shui,1,2 Hao Li,1,2 Guofu Zhou1,2 1Guangdong Provincial Key Laboratory of Optical Information Materials and Technology and Institute of Electronic Paper Displays, South China Academy of Advanced Optoelectronics, South China Normal University, Guangzhou, Guangdong 510006, 2National Center for International Research on Green Optoelectronics, South China Normal University, Guangzhou, Guangdong 510006, 3Department of Radiology, The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong 510405, China *These authors contributed equally to this work Abstract: Cancer has become one of the primary causes of death worldwide. Current cancer-therapy schemes are progressing relatively slowly in terms of reducing mortality, prolonging survival, time and enhancing cure rate, owing to the enormous obstacles of cancer pathophysiology. Therefore, specific diagnosis and therapy for malignant tumors are becoming more and more crucial and urgent, especially for early cancer diagnosis and cancer-targeted therapy. Derived theranostics that combine several functions into one “package” could further overcome undesirable differences in biodistribution and selectivity between distinct imaging and therapeutic agents. In this article, we discuss a chief clinical diagnosis tool – MRI – focusing on recent progress in magnetic agents or systems in multifunctional polymer nanoassemblies for combing cancer theranostics. We describe abundant polymeric MRI-contrast agents integrated with chemotherapy, gene therapy, thermotherapy, and radiotherapy, as well as other developing directions. Keywords: polymer, nanoassembly, magnetic resonance imaging, cancer theranosticsGan SLin YFeng YShui LLi HZhou GDove Medical PressarticlePolymerNanoassemblyMagnetic resonance imagingCancer theranosticsMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 13, Pp 4263-4281 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Polymer Nanoassembly Magnetic resonance imaging Cancer theranostics Medicine (General) R5-920
spellingShingle	Polymer Nanoassembly Magnetic resonance imaging Cancer theranostics Medicine (General) R5-920 Gan S Lin Y Feng Y Shui L Li H Zhou G Magnetic polymeric nanoassemblies for magnetic resonance imaging-combined cancer theranostics
description	Shenglong Gan,1,2,* Yisheng Lin,3,* Yancong Feng,1,2 Lingling Shui,1,2 Hao Li,1,2 Guofu Zhou1,2 1Guangdong Provincial Key Laboratory of Optical Information Materials and Technology and Institute of Electronic Paper Displays, South China Academy of Advanced Optoelectronics, South China Normal University, Guangzhou, Guangdong 510006, 2National Center for International Research on Green Optoelectronics, South China Normal University, Guangzhou, Guangdong 510006, 3Department of Radiology, The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong 510405, China *These authors contributed equally to this work Abstract: Cancer has become one of the primary causes of death worldwide. Current cancer-therapy schemes are progressing relatively slowly in terms of reducing mortality, prolonging survival, time and enhancing cure rate, owing to the enormous obstacles of cancer pathophysiology. Therefore, specific diagnosis and therapy for malignant tumors are becoming more and more crucial and urgent, especially for early cancer diagnosis and cancer-targeted therapy. Derived theranostics that combine several functions into one “package” could further overcome undesirable differences in biodistribution and selectivity between distinct imaging and therapeutic agents. In this article, we discuss a chief clinical diagnosis tool – MRI – focusing on recent progress in magnetic agents or systems in multifunctional polymer nanoassemblies for combing cancer theranostics. We describe abundant polymeric MRI-contrast agents integrated with chemotherapy, gene therapy, thermotherapy, and radiotherapy, as well as other developing directions. Keywords: polymer, nanoassembly, magnetic resonance imaging, cancer theranostics
format	article
author	Gan S Lin Y Feng Y Shui L Li H Zhou G
author_facet	Gan S Lin Y Feng Y Shui L Li H Zhou G
author_sort	Gan S
title	Magnetic polymeric nanoassemblies for magnetic resonance imaging-combined cancer theranostics
title_short	Magnetic polymeric nanoassemblies for magnetic resonance imaging-combined cancer theranostics
title_full	Magnetic polymeric nanoassemblies for magnetic resonance imaging-combined cancer theranostics
title_fullStr	Magnetic polymeric nanoassemblies for magnetic resonance imaging-combined cancer theranostics
title_full_unstemmed	Magnetic polymeric nanoassemblies for magnetic resonance imaging-combined cancer theranostics
title_sort	magnetic polymeric nanoassemblies for magnetic resonance imaging-combined cancer theranostics
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/4cb005dbb73346b8ac90826c5fd7ff1f
work_keys_str_mv	AT gans magneticpolymericnanoassembliesformagneticresonanceimagingcombinedcancertheranostics AT liny magneticpolymericnanoassembliesformagneticresonanceimagingcombinedcancertheranostics AT fengy magneticpolymericnanoassembliesformagneticresonanceimagingcombinedcancertheranostics AT shuil magneticpolymericnanoassembliesformagneticresonanceimagingcombinedcancertheranostics AT lih magneticpolymericnanoassembliesformagneticresonanceimagingcombinedcancertheranostics AT zhoug magneticpolymericnanoassembliesformagneticresonanceimagingcombinedcancertheranostics
_version_	1718399514752057344

Magnetic polymeric nanoassemblies for magnetic resonance imaging-combined cancer theranostics

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