Maternal insulin resistance multigenerationally impairs synaptic plasticity and memory via gametic mechanisms

Maternal insulin resistance multigenerationally impairs synaptic plasticity and memory via gametic mechanisms

It’s well known that hippocampal synaptic plasticity and memory are impaired in experimental models of metabolic diseases, however, it is unclear if maternal diet or metabolic alterations around the gestational age may multigenerationally affect learning and memory. In this study, authors demonstrat...

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Autores principales: Salvatore Fusco, Matteo Spinelli, Sara Cocco, Cristian Ripoli, Alessia Mastrodonato, Francesca Natale, Marco Rinaudo, Giulia Livrizzi, Claudio Grassi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/4cb241068bf443d786239ed236081505
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