IL-4-Producing Vγ1+/Vδ6+ γδ T Cells Sustain Germinal Center Reactions in Peyer’s Patches of Mice

IL-4-Producing Vγ1+/Vδ6+ γδ T Cells Sustain Germinal Center Reactions in Peyer’s Patches of Mice

The mucosal immune system is the first line of defense against pathogens. Germinal centers (GCs) in the Peyer’s patches (PPs) of the small intestine are constantly generated through stimulation of the microbiota. In this study, we investigated the role of γδ T cells in the GC reactions in PPs. Most...

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Bibliographic Details
Main Authors: Leon Ullrich, Yvonne Lueder, Anna-Lena Juergens, Anneke Wilharm, Joana Barros-Martins, Anja Bubke, Abdi Demera, Koichi Ikuta, Gwendolyn Elena Patzer, Anika Janssen, Inga Sandrock, Immo Prinz, Francesca Rampoldi
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
germinal center
Peyer’s patches
γδ T cells
Vγ1+ T cells
IL-4
IgA
Immunologic diseases. Allergy
RC581-607
Online Access:https://doaj.org/article/4cb32a24dbce4fc98e5a56dd8eee30a9
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