AMPK is involved in the regulation of incretin receptors expression in pancreatic islets under a low glucose concentration.

AMPK is involved in the regulation of incretin receptors expression in pancreatic islets under a low glucose concentration.

The precise role of AMP-activated protein kinase (AMPK), a target of metformin, in pancreatic β cells remains controversial, even though metformin was recently shown to enhance the expression of incretin receptors (GLP-1 and GIP receptors) in pancreatic β cells. In this study, we investigated the ef...

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Main Authors: Kazuki Tajima, Jun Shirakawa, Yu Togashi, Hideaki Inoue, Koichiro Sato, Kazuki Orime, Yuzuru Ito, Mitsuyo Kaji, Eri Sakamoto, Akinobu Nakamura, Kazutaka Aoki, Yoshio Goshima, Tatsuya Atsumi, Yasuo Terauchi
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/4cb8cb07151a472798dd6fc767ef136b
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https://doaj.org/article/4cb8cb07151a472798dd6fc767ef136b

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