Bradyarrhythmias secondary to topical levobunolol hydrochloride solution

Lianjun Lin,* Yuchuan Wang,* Yan Chen, Meilin Liu Geriatric Department, Peking University First Hospital, Beijing, People’s Republic of China *These authors contributed equally to this work Abstract: An 88-year-old man was admitted with fatigue, dizziness, and heart palpitations. Both t...

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Autores principales:	Lin LJ, Wang YC, Chen Y, Liu ML
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	bradycardia levobunolol hydrochloride topical beta-blocker Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/4cca0036358541b8a9a7d5eed0c4099b
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spelling	oai:doaj.org-article:4cca0036358541b8a9a7d5eed0c4099b2021-12-02T07:54:35ZBradyarrhythmias secondary to topical levobunolol hydrochloride solution1178-1998https://doaj.org/article/4cca0036358541b8a9a7d5eed0c4099b2014-10-01T00:00:00Zhttps://www.dovepress.com/bradyarrhythmias-secondary-to-topical-levobunolol-hydrochloride-soluti-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Lianjun Lin,* Yuchuan Wang,* Yan Chen, Meilin Liu Geriatric Department, Peking University First Hospital, Beijing, People’s Republic of China *These authors contributed equally to this work Abstract: An 88-year-old man was admitted with fatigue, dizziness, and heart palpitations. Both the electrocardiogram and Holter confirmed the existence of sinus bradycardia and sinus arrest. One hour prior to the onset of symptoms, he received levobunolol hydrochloride solution topically. The levobunolol hydrochloride solution was discontinued and the bradycardia resolved. He was diagnosed as having intermittent sinus bradycardia and sinus arrest, induced by topical ß-blocker therapy. Levobunolol hydrochloride solution is an effective therapy for ocular hypertension, probably by reducing aqueous fluid production. However, it can induce cardiac side effects such as bradyarrhythmia and should be used with caution in elderly patients or patients with cardiac disease. Keywords: bradycardia, topical ß-blocker, the elderly, glaucomaLin LJWang YCChen YLiu MLDove Medical Pressarticlebradycardialevobunolol hydrochloridetopical beta-blockerGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 9, Pp 1741-1745 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	bradycardia levobunolol hydrochloride topical beta-blocker Geriatrics RC952-954.6
spellingShingle	bradycardia levobunolol hydrochloride topical beta-blocker Geriatrics RC952-954.6 Lin LJ Wang YC Chen Y Liu ML Bradyarrhythmias secondary to topical levobunolol hydrochloride solution
description	Lianjun Lin,* Yuchuan Wang,* Yan Chen, Meilin Liu Geriatric Department, Peking University First Hospital, Beijing, People’s Republic of China *These authors contributed equally to this work Abstract: An 88-year-old man was admitted with fatigue, dizziness, and heart palpitations. Both the electrocardiogram and Holter confirmed the existence of sinus bradycardia and sinus arrest. One hour prior to the onset of symptoms, he received levobunolol hydrochloride solution topically. The levobunolol hydrochloride solution was discontinued and the bradycardia resolved. He was diagnosed as having intermittent sinus bradycardia and sinus arrest, induced by topical ß-blocker therapy. Levobunolol hydrochloride solution is an effective therapy for ocular hypertension, probably by reducing aqueous fluid production. However, it can induce cardiac side effects such as bradyarrhythmia and should be used with caution in elderly patients or patients with cardiac disease. Keywords: bradycardia, topical ß-blocker, the elderly, glaucoma
format	article
author	Lin LJ Wang YC Chen Y Liu ML
author_facet	Lin LJ Wang YC Chen Y Liu ML
author_sort	Lin LJ
title	Bradyarrhythmias secondary to topical levobunolol hydrochloride solution
title_short	Bradyarrhythmias secondary to topical levobunolol hydrochloride solution
title_full	Bradyarrhythmias secondary to topical levobunolol hydrochloride solution
title_fullStr	Bradyarrhythmias secondary to topical levobunolol hydrochloride solution
title_full_unstemmed	Bradyarrhythmias secondary to topical levobunolol hydrochloride solution
title_sort	bradyarrhythmias secondary to topical levobunolol hydrochloride solution
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/4cca0036358541b8a9a7d5eed0c4099b
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_version_	1718399101022765056

Bradyarrhythmias secondary to topical levobunolol hydrochloride solution

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