Association between modified CHA2DS2-VASc Score with Ankle-Brachial index < 0.9

Abstract The ankle-brachial index (ABI) is a reliable diagnostic examination for peripheral arterial occlusive disease (PAOD). We previously reported CHADS2 score was significantly correlated with PAOD. However, the association between CHA2DS2-VASc score and ABI < 0.9 is not evaluated in the lite...

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Autores principales:	Po-Chao Hsu, Wen-Hsien Lee, Hsiang-Chun Lee, Wei-Chung Tsai, Chun-Yuan Chu, Ying-Chih Chen, Chee-Siong Lee, Tsung-Hsien Lin, Wen-Chol Voon, Sheng-Hsiung Sheu, Ho-Ming Su
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/4ccbc574a4014e1b9ef32b048a6ec99b
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spelling	oai:doaj.org-article:4ccbc574a4014e1b9ef32b048a6ec99b2021-12-02T15:07:45ZAssociation between modified CHA2DS2-VASc Score with Ankle-Brachial index < 0.910.1038/s41598-018-19243-y2045-2322https://doaj.org/article/4ccbc574a4014e1b9ef32b048a6ec99b2018-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-19243-yhttps://doaj.org/toc/2045-2322Abstract The ankle-brachial index (ABI) is a reliable diagnostic examination for peripheral arterial occlusive disease (PAOD). We previously reported CHADS2 score was significantly correlated with PAOD. However, the association between CHA2DS2-VASc score and ABI < 0.9 is not evaluated in the literature. The aim of the present study was to investigate whether CHA2DS2-VASc score has a strong association with PAOD. We enrolled 1482 patients in this study. PAOD was defined as ABI < 0.9 in either leg. Vascular disease in CHA2DS2-VASc score was modified as vascular disease except PAOD. Of the 1482 subjects, the prevalence of ABI < 0.9 was 5.6%. Multivariate analysis showed that the increased age, decreased estimated glomerular filtration rate and increased modified CHA2DS2-VASc score (OR, 1.764; p < 0.001) were independent associated with ABI < 0.9. In addition, the percentage of ABI < 0.9 in patients with modified CHA2DS2-VASc score of 0, 1, and <2 were 0%, 0.9%, and 0.7%, respectively (All < 1%). Our study demonstrated modified CHA2DS2-VASc score was significantly associated with ABI < 0.9. Calculation of modified CHA2DS2-VASc score might be useful in identifying patients with PAOD and in stratifying the risk of PAOD in non-AF patients.Po-Chao HsuWen-Hsien LeeHsiang-Chun LeeWei-Chung TsaiChun-Yuan ChuYing-Chih ChenChee-Siong LeeTsung-Hsien LinWen-Chol VoonSheng-Hsiung SheuHo-Ming SuNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-6 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Po-Chao Hsu Wen-Hsien Lee Hsiang-Chun Lee Wei-Chung Tsai Chun-Yuan Chu Ying-Chih Chen Chee-Siong Lee Tsung-Hsien Lin Wen-Chol Voon Sheng-Hsiung Sheu Ho-Ming Su Association between modified CHA2DS2-VASc Score with Ankle-Brachial index < 0.9
description	Abstract The ankle-brachial index (ABI) is a reliable diagnostic examination for peripheral arterial occlusive disease (PAOD). We previously reported CHADS2 score was significantly correlated with PAOD. However, the association between CHA2DS2-VASc score and ABI < 0.9 is not evaluated in the literature. The aim of the present study was to investigate whether CHA2DS2-VASc score has a strong association with PAOD. We enrolled 1482 patients in this study. PAOD was defined as ABI < 0.9 in either leg. Vascular disease in CHA2DS2-VASc score was modified as vascular disease except PAOD. Of the 1482 subjects, the prevalence of ABI < 0.9 was 5.6%. Multivariate analysis showed that the increased age, decreased estimated glomerular filtration rate and increased modified CHA2DS2-VASc score (OR, 1.764; p < 0.001) were independent associated with ABI < 0.9. In addition, the percentage of ABI < 0.9 in patients with modified CHA2DS2-VASc score of 0, 1, and <2 were 0%, 0.9%, and 0.7%, respectively (All < 1%). Our study demonstrated modified CHA2DS2-VASc score was significantly associated with ABI < 0.9. Calculation of modified CHA2DS2-VASc score might be useful in identifying patients with PAOD and in stratifying the risk of PAOD in non-AF patients.
format	article
author	Po-Chao Hsu Wen-Hsien Lee Hsiang-Chun Lee Wei-Chung Tsai Chun-Yuan Chu Ying-Chih Chen Chee-Siong Lee Tsung-Hsien Lin Wen-Chol Voon Sheng-Hsiung Sheu Ho-Ming Su
author_facet	Po-Chao Hsu Wen-Hsien Lee Hsiang-Chun Lee Wei-Chung Tsai Chun-Yuan Chu Ying-Chih Chen Chee-Siong Lee Tsung-Hsien Lin Wen-Chol Voon Sheng-Hsiung Sheu Ho-Ming Su
author_sort	Po-Chao Hsu
title	Association between modified CHA2DS2-VASc Score with Ankle-Brachial index < 0.9
title_short	Association between modified CHA2DS2-VASc Score with Ankle-Brachial index < 0.9
title_full	Association between modified CHA2DS2-VASc Score with Ankle-Brachial index < 0.9
title_fullStr	Association between modified CHA2DS2-VASc Score with Ankle-Brachial index < 0.9
title_full_unstemmed	Association between modified CHA2DS2-VASc Score with Ankle-Brachial index < 0.9
title_sort	association between modified cha2ds2-vasc score with ankle-brachial index < 0.9
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/4ccbc574a4014e1b9ef32b048a6ec99b
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Association between modified CHA2DS2-VASc Score with Ankle-Brachial index < 0.9

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