Classifications within molecular subtypes enables identification of BRCA1/BRCA2 mutation carriers by RNA tumor profiling.

Classifications within molecular subtypes enables identification of BRCA1/BRCA2 mutation carriers by RNA tumor profiling.

Pathogenic germline mutations in BRCA1 or BRCA2 are detected in less than one third of families with a strong history of breast cancer. It is therefore expected that mutations still remain undetected by currently used screening methods. In addition, a growing number of BRCA1/2 sequence variants of u...

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Autores principales: Martin J Larsen, Torben A Kruse, Qihua Tan, Anne-Vibeke Lænkholm, Martin Bak, Anne E Lykkesfeldt, Kristina P Sørensen, Thomas V O Hansen, Bent Ejlertsen, Anne-Marie Gerdes, Mads Thomassen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/4ccdc704eb1c4c9e9250ec9c36bbdad8
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