Effects of Vibration Characteristics on the Atomization Performance in the Medical Piezoelectric Atomization Device Induced by Intra-Hole Fluctuation

Abstract Oral inhalation of aerosolized drugs has be widely applied in healing the affected body organs including lesions of the throat and lungs and it is more efficient than those conventional therapies, such as intravenous drip, intramuscular injection and external topical administration in the a...

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Autores principales:	Qiufeng Yan, Wanting Sun, Lei Zhang, Hongmei Wang, Jianhui Zhang
Formato:	article
Lenguaje:	EN
Publicado:	SpringerOpen 2021
Materias:	Piezoelectric Intra-hole fluctuation Vibration characteristics Atomization Ocean engineering TC1501-1800 Mechanical engineering and machinery TJ1-1570
Acceso en línea:	https://doaj.org/article/4ccead00159a4b9d8ad3a27c42146a8c
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spelling	oai:doaj.org-article:4ccead00159a4b9d8ad3a27c42146a8c2021-12-05T12:03:45ZEffects of Vibration Characteristics on the Atomization Performance in the Medical Piezoelectric Atomization Device Induced by Intra-Hole Fluctuation10.1186/s10033-021-00635-71000-93452192-8258https://doaj.org/article/4ccead00159a4b9d8ad3a27c42146a8c2021-12-01T00:00:00Zhttps://doi.org/10.1186/s10033-021-00635-7https://doaj.org/toc/1000-9345https://doaj.org/toc/2192-8258Abstract Oral inhalation of aerosolized drugs has be widely applied in healing the affected body organs including lesions of the throat and lungs and it is more efficient than those conventional therapies, such as intravenous drip, intramuscular injection and external topical administration in the aspects of the dosage reduction and side effects of drugs. Nevertheless, the traditional atomization devices always exhibit many drawbacks. For example, non-uniformed atomization particle distribution, the instability of transient atomization quantity and difficulties in precise energy control would seriously restrict an extensive use of atomization inhalation therapy. In this study, the principle of intra-hole fluctuation phenomenon occurred in the hole is fully explained, and the produced volume change is also estimated. Additionally, the mathematical expression of the atomization rate of the atomizing device is well established. The mechanism of the micro-pump is further clarified, and the influence of the vibration characteristics of the atomizing film on the atomization behavior is analyzed theoretically. The curves of sweep frequency against the velocity and amplitude of the piezoelectric vibrator are obtained by the Doppler laser vibrometer, and the corresponding mode shapes of the resonance point are achieved. The influence of vibration characteristics on atomization rate, atomization height and atomization particle size are also verified by experiments, respectively. Both the experimental results and theoretical calculation are expected to provide a guidance for the design of this kind of atomization device in the future.Qiufeng YanWanting SunLei ZhangHongmei WangJianhui ZhangSpringerOpenarticlePiezoelectricIntra-hole fluctuationVibration characteristicsAtomizationOcean engineeringTC1501-1800Mechanical engineering and machineryTJ1-1570ENChinese Journal of Mechanical Engineering, Vol 34, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Piezoelectric Intra-hole fluctuation Vibration characteristics Atomization Ocean engineering TC1501-1800 Mechanical engineering and machinery TJ1-1570
spellingShingle	Piezoelectric Intra-hole fluctuation Vibration characteristics Atomization Ocean engineering TC1501-1800 Mechanical engineering and machinery TJ1-1570 Qiufeng Yan Wanting Sun Lei Zhang Hongmei Wang Jianhui Zhang Effects of Vibration Characteristics on the Atomization Performance in the Medical Piezoelectric Atomization Device Induced by Intra-Hole Fluctuation
description	Abstract Oral inhalation of aerosolized drugs has be widely applied in healing the affected body organs including lesions of the throat and lungs and it is more efficient than those conventional therapies, such as intravenous drip, intramuscular injection and external topical administration in the aspects of the dosage reduction and side effects of drugs. Nevertheless, the traditional atomization devices always exhibit many drawbacks. For example, non-uniformed atomization particle distribution, the instability of transient atomization quantity and difficulties in precise energy control would seriously restrict an extensive use of atomization inhalation therapy. In this study, the principle of intra-hole fluctuation phenomenon occurred in the hole is fully explained, and the produced volume change is also estimated. Additionally, the mathematical expression of the atomization rate of the atomizing device is well established. The mechanism of the micro-pump is further clarified, and the influence of the vibration characteristics of the atomizing film on the atomization behavior is analyzed theoretically. The curves of sweep frequency against the velocity and amplitude of the piezoelectric vibrator are obtained by the Doppler laser vibrometer, and the corresponding mode shapes of the resonance point are achieved. The influence of vibration characteristics on atomization rate, atomization height and atomization particle size are also verified by experiments, respectively. Both the experimental results and theoretical calculation are expected to provide a guidance for the design of this kind of atomization device in the future.
format	article
author	Qiufeng Yan Wanting Sun Lei Zhang Hongmei Wang Jianhui Zhang
author_facet	Qiufeng Yan Wanting Sun Lei Zhang Hongmei Wang Jianhui Zhang
author_sort	Qiufeng Yan
title	Effects of Vibration Characteristics on the Atomization Performance in the Medical Piezoelectric Atomization Device Induced by Intra-Hole Fluctuation
title_short	Effects of Vibration Characteristics on the Atomization Performance in the Medical Piezoelectric Atomization Device Induced by Intra-Hole Fluctuation
title_full	Effects of Vibration Characteristics on the Atomization Performance in the Medical Piezoelectric Atomization Device Induced by Intra-Hole Fluctuation
title_fullStr	Effects of Vibration Characteristics on the Atomization Performance in the Medical Piezoelectric Atomization Device Induced by Intra-Hole Fluctuation
title_full_unstemmed	Effects of Vibration Characteristics on the Atomization Performance in the Medical Piezoelectric Atomization Device Induced by Intra-Hole Fluctuation
title_sort	effects of vibration characteristics on the atomization performance in the medical piezoelectric atomization device induced by intra-hole fluctuation
publisher	SpringerOpen
publishDate	2021
url	https://doaj.org/article/4ccead00159a4b9d8ad3a27c42146a8c
work_keys_str_mv	AT qiufengyan effectsofvibrationcharacteristicsontheatomizationperformanceinthemedicalpiezoelectricatomizationdeviceinducedbyintraholefluctuation AT wantingsun effectsofvibrationcharacteristicsontheatomizationperformanceinthemedicalpiezoelectricatomizationdeviceinducedbyintraholefluctuation AT leizhang effectsofvibrationcharacteristicsontheatomizationperformanceinthemedicalpiezoelectricatomizationdeviceinducedbyintraholefluctuation AT hongmeiwang effectsofvibrationcharacteristicsontheatomizationperformanceinthemedicalpiezoelectricatomizationdeviceinducedbyintraholefluctuation AT jianhuizhang effectsofvibrationcharacteristicsontheatomizationperformanceinthemedicalpiezoelectricatomizationdeviceinducedbyintraholefluctuation
_version_	1718372251635548160

Effects of Vibration Characteristics on the Atomization Performance in the Medical Piezoelectric Atomization Device Induced by Intra-Hole Fluctuation

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