Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer’s disease

Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer’s disease

Alzheimer’s disease (AD) is typically associated with hippocampal and cortical pathology, although hippocampal sparing and limbic predominant forms exist. The authors use transcriptomic analysis and neuropathology to identify genes associated with selective hippocampal vulnerability in AD.

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Autores principales: Angela M. Crist, Kelly M. Hinkle, Xue Wang, Christina M. Moloney, Billie J. Matchett, Sydney A. Labuzan, Isabelle Frankenhauser, Nkem O. Azu, Amanda M. Liesinger, Elizabeth R. Lesser, Daniel J. Serie, Zachary S. Quicksall, Tulsi A. Patel, Troy P. Carnwath, Michael DeTure, Xiaojia Tang, Ronald C. Petersen, Ranjan Duara, Neill R. Graff-Radford, Mariet Allen, Minerva M. Carrasquillo, Hu Li, Owen A. Ross, Nilüfer Ertekin-Taner, Dennis W. Dickson, Yan W. Asmann, Rickey E. Carter, Melissa E. Murray
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4cd05f374d8e492f8281dd38dc11f183
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spelling oai:doaj.org-article:4cd05f374d8e492f8281dd38dc11f1832021-12-02T18:28:38ZTranscriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer’s disease10.1038/s41467-021-22399-32041-1723https://doaj.org/article/4cd05f374d8e492f8281dd38dc11f1832021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22399-3https://doaj.org/toc/2041-1723Alzheimer’s disease (AD) is typically associated with hippocampal and cortical pathology, although hippocampal sparing and limbic predominant forms exist. The authors use transcriptomic analysis and neuropathology to identify genes associated with selective hippocampal vulnerability in AD.Angela M. CristKelly M. HinkleXue WangChristina M. MoloneyBillie J. MatchettSydney A. LabuzanIsabelle FrankenhauserNkem O. AzuAmanda M. LiesingerElizabeth R. LesserDaniel J. SerieZachary S. QuicksallTulsi A. PatelTroy P. CarnwathMichael DeTureXiaojia TangRonald C. PetersenRanjan DuaraNeill R. Graff-RadfordMariet AllenMinerva M. CarrasquilloHu LiOwen A. RossNilüfer Ertekin-TanerDennis W. DicksonYan W. AsmannRickey E. CarterMelissa E. MurrayNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Angela M. Crist
Kelly M. Hinkle
Xue Wang
Christina M. Moloney
Billie J. Matchett
Sydney A. Labuzan
Isabelle Frankenhauser
Nkem O. Azu
Amanda M. Liesinger
Elizabeth R. Lesser
Daniel J. Serie
Zachary S. Quicksall
Tulsi A. Patel
Troy P. Carnwath
Michael DeTure
Xiaojia Tang
Ronald C. Petersen
Ranjan Duara
Neill R. Graff-Radford
Mariet Allen
Minerva M. Carrasquillo
Hu Li
Owen A. Ross
Nilüfer Ertekin-Taner
Dennis W. Dickson
Yan W. Asmann
Rickey E. Carter
Melissa E. Murray
Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer’s disease
description Alzheimer’s disease (AD) is typically associated with hippocampal and cortical pathology, although hippocampal sparing and limbic predominant forms exist. The authors use transcriptomic analysis and neuropathology to identify genes associated with selective hippocampal vulnerability in AD.
format article
author Angela M. Crist
Kelly M. Hinkle
Xue Wang
Christina M. Moloney
Billie J. Matchett
Sydney A. Labuzan
Isabelle Frankenhauser
Nkem O. Azu
Amanda M. Liesinger
Elizabeth R. Lesser
Daniel J. Serie
Zachary S. Quicksall
Tulsi A. Patel
Troy P. Carnwath
Michael DeTure
Xiaojia Tang
Ronald C. Petersen
Ranjan Duara
Neill R. Graff-Radford
Mariet Allen
Minerva M. Carrasquillo
Hu Li
Owen A. Ross
Nilüfer Ertekin-Taner
Dennis W. Dickson
Yan W. Asmann
Rickey E. Carter
Melissa E. Murray
author_facet Angela M. Crist
Kelly M. Hinkle
Xue Wang
Christina M. Moloney
Billie J. Matchett
Sydney A. Labuzan
Isabelle Frankenhauser
Nkem O. Azu
Amanda M. Liesinger
Elizabeth R. Lesser
Daniel J. Serie
Zachary S. Quicksall
Tulsi A. Patel
Troy P. Carnwath
Michael DeTure
Xiaojia Tang
Ronald C. Petersen
Ranjan Duara
Neill R. Graff-Radford
Mariet Allen
Minerva M. Carrasquillo
Hu Li
Owen A. Ross
Nilüfer Ertekin-Taner
Dennis W. Dickson
Yan W. Asmann
Rickey E. Carter
Melissa E. Murray
author_sort Angela M. Crist
title Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer’s disease
title_short Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer’s disease
title_full Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer’s disease
title_fullStr Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer’s disease
title_full_unstemmed Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer’s disease
title_sort transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in alzheimer’s disease
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/4cd05f374d8e492f8281dd38dc11f183
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