Value of susceptibility weighted imaging (SWI) in assessment of intra-arterial thrombus in patients with acute ischemic stroke

Abstract Background Ischemic stroke is a major cause of death and disability. Thrombolytic therapy is a standard treatment stroke nowadays for ischemic strokes up to 4.5 h from start of symptoms. Although arterial occlusion can be detected by digital subtraction angiography (DSA), magnetic resonance...

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Autores principales:	Ehab Ali Abdelgawad, Mohammed F. Amin, Ahmed Abdellatif, Mohamed Aboulfotoh Mourad, Manal F. Abusamra
Formato:	article
Lenguaje:	EN
Publicado:	SpringerOpen 2021
Materias:	MRI SWI MRA Medical physics. Medical radiology. Nuclear medicine R895-920
Acceso en línea:	https://doaj.org/article/4cda071e238b4dada29df3fc086d3f15
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spelling	oai:doaj.org-article:4cda071e238b4dada29df3fc086d3f152021-11-14T12:27:10ZValue of susceptibility weighted imaging (SWI) in assessment of intra-arterial thrombus in patients with acute ischemic stroke10.1186/s43055-021-00649-02090-4762https://doaj.org/article/4cda071e238b4dada29df3fc086d3f152021-11-01T00:00:00Zhttps://doi.org/10.1186/s43055-021-00649-0https://doaj.org/toc/2090-4762Abstract Background Ischemic stroke is a major cause of death and disability. Thrombolytic therapy is a standard treatment stroke nowadays for ischemic strokes up to 4.5 h from start of symptoms. Although arterial occlusion can be detected by digital subtraction angiography (DSA), magnetic resonance angiography (MRA), and computed tomography angiography (CTA), the question about thrombus composition and formation times still might not be replied. The use of susceptibility weighted imaging (SWI) for detecting thrombus in acute ischemic stroke is getting to be a strongly investigated field. SWI can show the thrombus as a hypointense susceptibility vessel sign (SVS) in the affected area. Results Ninety-seven of our patients showed thrombus in MRA study. M1 segment was the most affected MCA segment representing about 57.6%. SWI detected intra-arterial thrombus in 122 patients compared to 97 patients detected by MRA (P = 0.0002). All patients had positive susceptibility sign. 88.8% of patients with positive thrombus in SWI had solitary thrombus, and 11.2% has multiple thrombi; on the other hand, MRA fails to detect any distant thrombi. 81% of patients with abnormally prominent vessel sign (APVS) showed parenchymal changes in these areas. On the other hand, deep structures, namely caudate nucleus, internal capsule and lentiform nucleus, are the least affected areas. All patients with abnormally prominent vessel sign showed arterial occlusion, and only 9 patients with no APVS showed arterial occlusion (P = 0.0001). Conclusion SWI plays an important role in the detection of peripheral thrombi in patients with acute ischemic stroke. Both SWI and MRA might complement each other for visual detection of occluded vessel. We recommend implementation of SWI into routine acute stroke MRI protocols.Ehab Ali AbdelgawadMohammed F. AminAhmed AbdellatifMohamed Aboulfotoh MouradManal F. AbusamraSpringerOpenarticleMRISWIMRAMedical physics. Medical radiology. Nuclear medicineR895-920ENThe Egyptian Journal of Radiology and Nuclear Medicine, Vol 52, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	MRI SWI MRA Medical physics. Medical radiology. Nuclear medicine R895-920
spellingShingle	MRI SWI MRA Medical physics. Medical radiology. Nuclear medicine R895-920 Ehab Ali Abdelgawad Mohammed F. Amin Ahmed Abdellatif Mohamed Aboulfotoh Mourad Manal F. Abusamra Value of susceptibility weighted imaging (SWI) in assessment of intra-arterial thrombus in patients with acute ischemic stroke
description	Abstract Background Ischemic stroke is a major cause of death and disability. Thrombolytic therapy is a standard treatment stroke nowadays for ischemic strokes up to 4.5 h from start of symptoms. Although arterial occlusion can be detected by digital subtraction angiography (DSA), magnetic resonance angiography (MRA), and computed tomography angiography (CTA), the question about thrombus composition and formation times still might not be replied. The use of susceptibility weighted imaging (SWI) for detecting thrombus in acute ischemic stroke is getting to be a strongly investigated field. SWI can show the thrombus as a hypointense susceptibility vessel sign (SVS) in the affected area. Results Ninety-seven of our patients showed thrombus in MRA study. M1 segment was the most affected MCA segment representing about 57.6%. SWI detected intra-arterial thrombus in 122 patients compared to 97 patients detected by MRA (P = 0.0002). All patients had positive susceptibility sign. 88.8% of patients with positive thrombus in SWI had solitary thrombus, and 11.2% has multiple thrombi; on the other hand, MRA fails to detect any distant thrombi. 81% of patients with abnormally prominent vessel sign (APVS) showed parenchymal changes in these areas. On the other hand, deep structures, namely caudate nucleus, internal capsule and lentiform nucleus, are the least affected areas. All patients with abnormally prominent vessel sign showed arterial occlusion, and only 9 patients with no APVS showed arterial occlusion (P = 0.0001). Conclusion SWI plays an important role in the detection of peripheral thrombi in patients with acute ischemic stroke. Both SWI and MRA might complement each other for visual detection of occluded vessel. We recommend implementation of SWI into routine acute stroke MRI protocols.
format	article
author	Ehab Ali Abdelgawad Mohammed F. Amin Ahmed Abdellatif Mohamed Aboulfotoh Mourad Manal F. Abusamra
author_facet	Ehab Ali Abdelgawad Mohammed F. Amin Ahmed Abdellatif Mohamed Aboulfotoh Mourad Manal F. Abusamra
author_sort	Ehab Ali Abdelgawad
title	Value of susceptibility weighted imaging (SWI) in assessment of intra-arterial thrombus in patients with acute ischemic stroke
title_short	Value of susceptibility weighted imaging (SWI) in assessment of intra-arterial thrombus in patients with acute ischemic stroke
title_full	Value of susceptibility weighted imaging (SWI) in assessment of intra-arterial thrombus in patients with acute ischemic stroke
title_fullStr	Value of susceptibility weighted imaging (SWI) in assessment of intra-arterial thrombus in patients with acute ischemic stroke
title_full_unstemmed	Value of susceptibility weighted imaging (SWI) in assessment of intra-arterial thrombus in patients with acute ischemic stroke
title_sort	value of susceptibility weighted imaging (swi) in assessment of intra-arterial thrombus in patients with acute ischemic stroke
publisher	SpringerOpen
publishDate	2021
url	https://doaj.org/article/4cda071e238b4dada29df3fc086d3f15
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Value of susceptibility weighted imaging (SWI) in assessment of intra-arterial thrombus in patients with acute ischemic stroke

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