Adverse Events Following COVID-19 Vaccine in Patients Previously Injected with Facial Filler: Scoping Review and Case Report

The “Vaccines and Related Biological Products Advisory Committee 17 December 2020 Meeting Briefing Document”, formulated by the FDA, reported three cases of swelling in areas previously injected with HA filler, introducing the possible relationship between a COVID-19 vaccine and adverse events in ar...

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Autores principales: Raffaele Rauso, Giorgio Lo Giudice, Nicola Zerbinati, Giovanni Francesco Nicoletti, Romolo Fragola, Gianpaolo Tartaro
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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spelling oai:doaj.org-article:4ce193a4fd904da1952162e2e0972afe2021-11-25T16:39:52ZAdverse Events Following COVID-19 Vaccine in Patients Previously Injected with Facial Filler: Scoping Review and Case Report10.3390/app1122108882076-3417https://doaj.org/article/4ce193a4fd904da1952162e2e0972afe2021-11-01T00:00:00Zhttps://www.mdpi.com/2076-3417/11/22/10888https://doaj.org/toc/2076-3417The “Vaccines and Related Biological Products Advisory Committee 17 December 2020 Meeting Briefing Document”, formulated by the FDA, reported three cases of swelling in areas previously injected with HA filler, introducing the possible relationship between a COVID-19 vaccine and adverse events in areas previously injected with HA fillers. The aim of this research is to report a case of an adverse event following a COVID-19 vaccine in a patient previously injected with facial filler. Furthermore, a scoping review on the same topic was performed. The research was carried out on the electronic databases PubMed, Cochrane Library, Web of Science, Google Scholar and Scopus. The selection process identified four articles as eligible for inclusion in the review. Nineteen patients, including the described case report, who experienced an adverse event following a COVID-19 vaccine in areas previously injected with facial filler were identified. Adverse events following a COVID-19 vaccine in patients previously injected with facial filler appear to be rare. A high BDDE cross-linking rate and/or a low-molecular-weight hyaluronic acid filler may have a higher tardive adverse event rate when triggered.Raffaele RausoGiorgio Lo GiudiceNicola ZerbinatiGiovanni Francesco NicolettiRomolo FragolaGianpaolo TartaroMDPI AGarticlefillerhyaluronic acidadverse reactionCOVID-19COVID-19 vaccinesSARS-CoV-2TechnologyTEngineering (General). Civil engineering (General)TA1-2040Biology (General)QH301-705.5PhysicsQC1-999ChemistryQD1-999ENApplied Sciences, Vol 11, Iss 10888, p 10888 (2021)
institution DOAJ
collection DOAJ
language EN
topic filler
hyaluronic acid
adverse reaction
COVID-19
COVID-19 vaccines
SARS-CoV-2
Technology
T
Engineering (General). Civil engineering (General)
TA1-2040
Biology (General)
QH301-705.5
Physics
QC1-999
Chemistry
QD1-999
spellingShingle filler
hyaluronic acid
adverse reaction
COVID-19
COVID-19 vaccines
SARS-CoV-2
Technology
T
Engineering (General). Civil engineering (General)
TA1-2040
Biology (General)
QH301-705.5
Physics
QC1-999
Chemistry
QD1-999
Raffaele Rauso
Giorgio Lo Giudice
Nicola Zerbinati
Giovanni Francesco Nicoletti
Romolo Fragola
Gianpaolo Tartaro
Adverse Events Following COVID-19 Vaccine in Patients Previously Injected with Facial Filler: Scoping Review and Case Report
description The “Vaccines and Related Biological Products Advisory Committee 17 December 2020 Meeting Briefing Document”, formulated by the FDA, reported three cases of swelling in areas previously injected with HA filler, introducing the possible relationship between a COVID-19 vaccine and adverse events in areas previously injected with HA fillers. The aim of this research is to report a case of an adverse event following a COVID-19 vaccine in a patient previously injected with facial filler. Furthermore, a scoping review on the same topic was performed. The research was carried out on the electronic databases PubMed, Cochrane Library, Web of Science, Google Scholar and Scopus. The selection process identified four articles as eligible for inclusion in the review. Nineteen patients, including the described case report, who experienced an adverse event following a COVID-19 vaccine in areas previously injected with facial filler were identified. Adverse events following a COVID-19 vaccine in patients previously injected with facial filler appear to be rare. A high BDDE cross-linking rate and/or a low-molecular-weight hyaluronic acid filler may have a higher tardive adverse event rate when triggered.
format article
author Raffaele Rauso
Giorgio Lo Giudice
Nicola Zerbinati
Giovanni Francesco Nicoletti
Romolo Fragola
Gianpaolo Tartaro
author_facet Raffaele Rauso
Giorgio Lo Giudice
Nicola Zerbinati
Giovanni Francesco Nicoletti
Romolo Fragola
Gianpaolo Tartaro
author_sort Raffaele Rauso
title Adverse Events Following COVID-19 Vaccine in Patients Previously Injected with Facial Filler: Scoping Review and Case Report
title_short Adverse Events Following COVID-19 Vaccine in Patients Previously Injected with Facial Filler: Scoping Review and Case Report
title_full Adverse Events Following COVID-19 Vaccine in Patients Previously Injected with Facial Filler: Scoping Review and Case Report
title_fullStr Adverse Events Following COVID-19 Vaccine in Patients Previously Injected with Facial Filler: Scoping Review and Case Report
title_full_unstemmed Adverse Events Following COVID-19 Vaccine in Patients Previously Injected with Facial Filler: Scoping Review and Case Report
title_sort adverse events following covid-19 vaccine in patients previously injected with facial filler: scoping review and case report
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/4ce193a4fd904da1952162e2e0972afe
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