Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters

The MuvB complex, which regulates cell cycle dependent gene expression, binds promoter cell cycle genes homology region (CHR) elements. Here the authors solve the structure of LIN54, a component of MuvB, bound to DNA and use it to explain the recognition of a CHR sequence.

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Autores principales:	Aimee H. Marceau, Jessica G. Felthousen, Paul D. Goetsch, Audra N. Iness, Hsiau-Wei Lee, Sarvind M. Tripathi, Susan Strome, Larisa Litovchick, Seth M. Rubin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4ce47b47d36e4e24bddd06139f1e4c75
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spelling	oai:doaj.org-article:4ce47b47d36e4e24bddd06139f1e4c752021-12-02T14:39:11ZStructural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters10.1038/ncomms123012041-1723https://doaj.org/article/4ce47b47d36e4e24bddd06139f1e4c752016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12301https://doaj.org/toc/2041-1723The MuvB complex, which regulates cell cycle dependent gene expression, binds promoter cell cycle genes homology region (CHR) elements. Here the authors solve the structure of LIN54, a component of MuvB, bound to DNA and use it to explain the recognition of a CHR sequence.Aimee H. MarceauJessica G. FelthousenPaul D. GoetschAudra N. InessHsiau-Wei LeeSarvind M. TripathiSusan StromeLarisa LitovchickSeth M. RubinNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Aimee H. Marceau Jessica G. Felthousen Paul D. Goetsch Audra N. Iness Hsiau-Wei Lee Sarvind M. Tripathi Susan Strome Larisa Litovchick Seth M. Rubin Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters
description	The MuvB complex, which regulates cell cycle dependent gene expression, binds promoter cell cycle genes homology region (CHR) elements. Here the authors solve the structure of LIN54, a component of MuvB, bound to DNA and use it to explain the recognition of a CHR sequence.
format	article
author	Aimee H. Marceau Jessica G. Felthousen Paul D. Goetsch Audra N. Iness Hsiau-Wei Lee Sarvind M. Tripathi Susan Strome Larisa Litovchick Seth M. Rubin
author_facet	Aimee H. Marceau Jessica G. Felthousen Paul D. Goetsch Audra N. Iness Hsiau-Wei Lee Sarvind M. Tripathi Susan Strome Larisa Litovchick Seth M. Rubin
author_sort	Aimee H. Marceau
title	Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters
title_short	Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters
title_full	Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters
title_fullStr	Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters
title_full_unstemmed	Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters
title_sort	structural basis for lin54 recognition of chr elements in cell cycle-regulated promoters
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/4ce47b47d36e4e24bddd06139f1e4c75
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Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters

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