Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters

Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters

The MuvB complex, which regulates cell cycle dependent gene expression, binds promoter cell cycle genes homology region (CHR) elements. Here the authors solve the structure of LIN54, a component of MuvB, bound to DNA and use it to explain the recognition of a CHR sequence.

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Detalles Bibliográficos
Autores principales: Aimee H. Marceau, Jessica G. Felthousen, Paul D. Goetsch, Audra N. Iness, Hsiau-Wei Lee, Sarvind M. Tripathi, Susan Strome, Larisa Litovchick, Seth M. Rubin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/4ce47b47d36e4e24bddd06139f1e4c75
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