HTLV-1 bZIP factor suppresses TDP1 expression through inhibition of NRF-1 in adult T-cell leukemia
Abstract Adult T-cell leukemia (ATL) is an aggressive T-cell malignancy caused by human T-cell leukemia virus type 1 (HTLV-1). We recently reported that abacavir, an anti-HIV-1 drug, potently and selectively kills ATL cells. This effect was attributed to the reduced expression of tyrosyl-DNA-phospho...
Enregistré dans:
Auteurs principaux: | Yoko Takiuchi, Masayuki Kobayashi, Kohei Tada, Fumie Iwai, Maki Sakurada, Shigeki Hirabayashi, Kayoko Nagata, Kotaro Shirakawa, Keisuke Shindo, Jun-ichirou Yasunaga, Yasuhiro Murakawa, Vinodh Rajapakse, Yves Pommier, Masao Matsuoka, Akifumi Takaori-Kondo |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/4ce52dd39fc841c4b3f83bf6d24a6459 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo.
par: Yorifumi Satou, et autres
Publié: (2011) -
HTLV-1 bZIP factor induces inflammation through labile Foxp3 expression.
par: Nanae Yamamoto-Taguchi, et autres
Publié: (2013) -
The Nrf1 CNC-bZIP protein is regulated by the proteasome and activated by hypoxia.
par: Nikolai L Chepelev, et autres
Publié: (2011) -
The bZIP Transcription Factor ZIP-11 Is Required for the Innate Immune Regulation in Caenorhabditis elegans
par: Zhongfan Zheng, et autres
Publié: (2021) -
The bZIP transcription factor Fgap1 mediates oxidative stress response and trichothecene biosynthesis but not virulence in Fusarium graminearum.
par: Mathilde Montibus, et autres
Publié: (2013)