Blood banking in living droplets.
Blood banking has a broad public health impact influencing millions of lives daily. It could potentially benefit from emerging biopreservation technologies. However, although vitrification has shown advantages over traditional cryopreservation techniques, it has not been incorporated into transfusio...
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Public Library of Science (PLoS)
2011
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| Acceso en línea: | https://doaj.org/article/4cf2fb7eca2646d2808ac6a243ee7091 |
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oai:doaj.org-article:4cf2fb7eca2646d2808ac6a243ee70912021-11-18T06:57:26ZBlood banking in living droplets.1932-620310.1371/journal.pone.0017530https://doaj.org/article/4cf2fb7eca2646d2808ac6a243ee70912011-03-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21412411/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Blood banking has a broad public health impact influencing millions of lives daily. It could potentially benefit from emerging biopreservation technologies. However, although vitrification has shown advantages over traditional cryopreservation techniques, it has not been incorporated into transfusion medicine mainly due to throughput challenges. Here, we present a scalable method that can vitrify red blood cells in microdroplets. This approach enables the vitrification of large volumes of blood in a short amount of time, and makes it a viable and scalable biotechnology tool for blood cryopreservation.Josh SamotSangjun MoonLei ShaoXiaohui ZhangFeng XuYoungseok SongHasan Onur KelesHasan Onur KelesLaura MatloffJordan MarkelUtkan DemirciPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 6, Iss 3, p e17530 (2011) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Medicine R Science Q |
| spellingShingle |
Medicine R Science Q Josh Samot Sangjun Moon Lei Shao Xiaohui Zhang Feng Xu Youngseok Song Hasan Onur Keles Hasan Onur Keles Laura Matloff Jordan Markel Utkan Demirci Blood banking in living droplets. |
| description |
Blood banking has a broad public health impact influencing millions of lives daily. It could potentially benefit from emerging biopreservation technologies. However, although vitrification has shown advantages over traditional cryopreservation techniques, it has not been incorporated into transfusion medicine mainly due to throughput challenges. Here, we present a scalable method that can vitrify red blood cells in microdroplets. This approach enables the vitrification of large volumes of blood in a short amount of time, and makes it a viable and scalable biotechnology tool for blood cryopreservation. |
| format |
article |
| author |
Josh Samot Sangjun Moon Lei Shao Xiaohui Zhang Feng Xu Youngseok Song Hasan Onur Keles Hasan Onur Keles Laura Matloff Jordan Markel Utkan Demirci |
| author_facet |
Josh Samot Sangjun Moon Lei Shao Xiaohui Zhang Feng Xu Youngseok Song Hasan Onur Keles Hasan Onur Keles Laura Matloff Jordan Markel Utkan Demirci |
| author_sort |
Josh Samot |
| title |
Blood banking in living droplets. |
| title_short |
Blood banking in living droplets. |
| title_full |
Blood banking in living droplets. |
| title_fullStr |
Blood banking in living droplets. |
| title_full_unstemmed |
Blood banking in living droplets. |
| title_sort |
blood banking in living droplets. |
| publisher |
Public Library of Science (PLoS) |
| publishDate |
2011 |
| url |
https://doaj.org/article/4cf2fb7eca2646d2808ac6a243ee7091 |
| work_keys_str_mv |
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1718424165102387200 |