Variation in the susceptibility of urban Aedes mosquitoes infected with a densovirus

Abstract Urban Aedes mosquitoes are vectors of many viruses affecting human health such as dengue, chikungunya and Zika viruses. Insecticide resistance and environmental toxicity risks hamper the effectiveness of chemical control against these mosquito vectors. Alternative control methods, such as t...

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Autores principales:	Aurélie Perrin, Anne-Sophie Gosselin-Grenet, Marie Rossignol, Carole Ginibre, Bethsabée Scheid, Christophe Lagneau, Fabrice Chandre, Thierry Baldet, Mylène Ogliastro, Jérémy Bouyer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/4cfa0373c86c4c09923ac6be8654d495
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spelling	oai:doaj.org-article:4cfa0373c86c4c09923ac6be8654d4952021-12-02T15:10:11ZVariation in the susceptibility of urban Aedes mosquitoes infected with a densovirus10.1038/s41598-020-75765-42045-2322https://doaj.org/article/4cfa0373c86c4c09923ac6be8654d4952020-10-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-75765-4https://doaj.org/toc/2045-2322Abstract Urban Aedes mosquitoes are vectors of many viruses affecting human health such as dengue, chikungunya and Zika viruses. Insecticide resistance and environmental toxicity risks hamper the effectiveness of chemical control against these mosquito vectors. Alternative control methods, such as the use of mosquito-specific entomopathogenic viruses should be explored. Numerous studies have focused on evaluating the potential of different densoviruses species as biological control agents. However, knowledge on the extent of inter- and intra-specific variations in the susceptibility of Aedes mosquitoes to infection by different densoviruses remains insufficient. In this study, we compared infection and mortality rates induced by the Aedes albopictus densovirus 2 in different strains of Aedes albopictus and Aedes aegypti mosquitoes. The two Aedes species were different in terms of susceptibility to viral infection. Under laboratory conditions, Aedes albopictus densovirus 2 appeared more virulent for the different strains of Aedes aegypti tested than for those of Aedes albopictus. In addition, we also found significant intra-specific variation in infection and mortality rates. Thus, although even if Aedes albopictus densoviruses could be powerful biocontrol agents used in the management of urban Aedes populations, our results also call into question the use of single viral isolate as biocontrol agents.Aurélie PerrinAnne-Sophie Gosselin-GrenetMarie RossignolCarole GinibreBethsabée ScheidChristophe LagneauFabrice ChandreThierry BaldetMylène OgliastroJérémy BouyerNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Aurélie Perrin Anne-Sophie Gosselin-Grenet Marie Rossignol Carole Ginibre Bethsabée Scheid Christophe Lagneau Fabrice Chandre Thierry Baldet Mylène Ogliastro Jérémy Bouyer Variation in the susceptibility of urban Aedes mosquitoes infected with a densovirus
description	Abstract Urban Aedes mosquitoes are vectors of many viruses affecting human health such as dengue, chikungunya and Zika viruses. Insecticide resistance and environmental toxicity risks hamper the effectiveness of chemical control against these mosquito vectors. Alternative control methods, such as the use of mosquito-specific entomopathogenic viruses should be explored. Numerous studies have focused on evaluating the potential of different densoviruses species as biological control agents. However, knowledge on the extent of inter- and intra-specific variations in the susceptibility of Aedes mosquitoes to infection by different densoviruses remains insufficient. In this study, we compared infection and mortality rates induced by the Aedes albopictus densovirus 2 in different strains of Aedes albopictus and Aedes aegypti mosquitoes. The two Aedes species were different in terms of susceptibility to viral infection. Under laboratory conditions, Aedes albopictus densovirus 2 appeared more virulent for the different strains of Aedes aegypti tested than for those of Aedes albopictus. In addition, we also found significant intra-specific variation in infection and mortality rates. Thus, although even if Aedes albopictus densoviruses could be powerful biocontrol agents used in the management of urban Aedes populations, our results also call into question the use of single viral isolate as biocontrol agents.
format	article
author	Aurélie Perrin Anne-Sophie Gosselin-Grenet Marie Rossignol Carole Ginibre Bethsabée Scheid Christophe Lagneau Fabrice Chandre Thierry Baldet Mylène Ogliastro Jérémy Bouyer
author_facet	Aurélie Perrin Anne-Sophie Gosselin-Grenet Marie Rossignol Carole Ginibre Bethsabée Scheid Christophe Lagneau Fabrice Chandre Thierry Baldet Mylène Ogliastro Jérémy Bouyer
author_sort	Aurélie Perrin
title	Variation in the susceptibility of urban Aedes mosquitoes infected with a densovirus
title_short	Variation in the susceptibility of urban Aedes mosquitoes infected with a densovirus
title_full	Variation in the susceptibility of urban Aedes mosquitoes infected with a densovirus
title_fullStr	Variation in the susceptibility of urban Aedes mosquitoes infected with a densovirus
title_full_unstemmed	Variation in the susceptibility of urban Aedes mosquitoes infected with a densovirus
title_sort	variation in the susceptibility of urban aedes mosquitoes infected with a densovirus
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/4cfa0373c86c4c09923ac6be8654d495
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Variation in the susceptibility of urban Aedes mosquitoes infected with a densovirus

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