Alopecia Areata Incognita and Diffuse Alopecia Areata: Clinical, Trichoscopic, Histopathological, and Therapeutic Features of a 5-Year Study

Background: Alopecia areata is a nonscarring hair loss that usually causes round patches of baldness, but alopecia areata incognita (AAI) and diffuse alopecia areata (DAA) can cause a diffuse and acute pattern of hair loss. Objective: To analyze the clinical, trichoscopic, histological, and ther...

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Autores principales: Aurora Alessandrini, Michela Starace, Francesca Bruni, Nicolò Brandi, Carlotta Baraldi, Cosimo Misciali, Pier Alessandro Fanti, Bianca Maria Piraccini
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Publicado: Mattioli1885 2019
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spelling oai:doaj.org-article:4cfc0b4165e84f17b99eb2d432fcadb42021-11-17T08:29:09ZAlopecia Areata Incognita and Diffuse Alopecia Areata: Clinical, Trichoscopic, Histopathological, and Therapeutic Features of a 5-Year Study10.5826/dpc.0904a052160-9381https://doaj.org/article/4cfc0b4165e84f17b99eb2d432fcadb42019-10-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/869https://doaj.org/toc/2160-9381 Background: Alopecia areata is a nonscarring hair loss that usually causes round patches of baldness, but alopecia areata incognita (AAI) and diffuse alopecia areata (DAA) can cause a diffuse and acute pattern of hair loss. Objective: To analyze the clinical, trichoscopic, histological, and therapeutic features of AAI and DAA. Methods: The study was designed to include data of patients with histological diagnosis of AAI and DAA enrolled in our Hair Disease Outpatient Consultations. Results: DAA had a greater involvement of the parietal and anterior-temporal regions, while AAI manifested itself mainly in the occipital-parietal regions. The most frequent pattern was empty yellow dots, yellow dots with vellus hairs, and small hair in regrowth, but the presence of pigtail hair was found almost exclusively in those with AAI. In cases of DDA, the finding of dystrophic hair and black dots was more frequent. The most frequent trichoscopic sign in both diseases was the presence of empty yellow dots, which, however, were described in a higher percentage in cases of DAA. The diseases have a benign course and are responsive to topical steroid therapy. Conclusions: Trichoscopy is very important for the differential diagnosis between the 2 diseases and to select the best site for biopsy. In the presence of diffuse hair thinning, these entities must be considered. Aurora AlessandriniMichela StaraceFrancesca BruniNicolò BrandiCarlotta BaraldiCosimo MiscialiPier Alessandro FantiBianca Maria PiracciniMattioli1885articlealopecia areata incognitadiffuse alopecia areatayellow dotshistopathologytherapyDermatologyRL1-803ENDermatology Practical & Conceptual, Vol 9, Iss 4 (2019)
institution DOAJ
collection DOAJ
language EN
topic alopecia areata incognita
diffuse alopecia areata
yellow dots
histopathology
therapy
Dermatology
RL1-803
spellingShingle alopecia areata incognita
diffuse alopecia areata
yellow dots
histopathology
therapy
Dermatology
RL1-803
Aurora Alessandrini
Michela Starace
Francesca Bruni
Nicolò Brandi
Carlotta Baraldi
Cosimo Misciali
Pier Alessandro Fanti
Bianca Maria Piraccini
Alopecia Areata Incognita and Diffuse Alopecia Areata: Clinical, Trichoscopic, Histopathological, and Therapeutic Features of a 5-Year Study
description Background: Alopecia areata is a nonscarring hair loss that usually causes round patches of baldness, but alopecia areata incognita (AAI) and diffuse alopecia areata (DAA) can cause a diffuse and acute pattern of hair loss. Objective: To analyze the clinical, trichoscopic, histological, and therapeutic features of AAI and DAA. Methods: The study was designed to include data of patients with histological diagnosis of AAI and DAA enrolled in our Hair Disease Outpatient Consultations. Results: DAA had a greater involvement of the parietal and anterior-temporal regions, while AAI manifested itself mainly in the occipital-parietal regions. The most frequent pattern was empty yellow dots, yellow dots with vellus hairs, and small hair in regrowth, but the presence of pigtail hair was found almost exclusively in those with AAI. In cases of DDA, the finding of dystrophic hair and black dots was more frequent. The most frequent trichoscopic sign in both diseases was the presence of empty yellow dots, which, however, were described in a higher percentage in cases of DAA. The diseases have a benign course and are responsive to topical steroid therapy. Conclusions: Trichoscopy is very important for the differential diagnosis between the 2 diseases and to select the best site for biopsy. In the presence of diffuse hair thinning, these entities must be considered.
format article
author Aurora Alessandrini
Michela Starace
Francesca Bruni
Nicolò Brandi
Carlotta Baraldi
Cosimo Misciali
Pier Alessandro Fanti
Bianca Maria Piraccini
author_facet Aurora Alessandrini
Michela Starace
Francesca Bruni
Nicolò Brandi
Carlotta Baraldi
Cosimo Misciali
Pier Alessandro Fanti
Bianca Maria Piraccini
author_sort Aurora Alessandrini
title Alopecia Areata Incognita and Diffuse Alopecia Areata: Clinical, Trichoscopic, Histopathological, and Therapeutic Features of a 5-Year Study
title_short Alopecia Areata Incognita and Diffuse Alopecia Areata: Clinical, Trichoscopic, Histopathological, and Therapeutic Features of a 5-Year Study
title_full Alopecia Areata Incognita and Diffuse Alopecia Areata: Clinical, Trichoscopic, Histopathological, and Therapeutic Features of a 5-Year Study
title_fullStr Alopecia Areata Incognita and Diffuse Alopecia Areata: Clinical, Trichoscopic, Histopathological, and Therapeutic Features of a 5-Year Study
title_full_unstemmed Alopecia Areata Incognita and Diffuse Alopecia Areata: Clinical, Trichoscopic, Histopathological, and Therapeutic Features of a 5-Year Study
title_sort alopecia areata incognita and diffuse alopecia areata: clinical, trichoscopic, histopathological, and therapeutic features of a 5-year study
publisher Mattioli1885
publishDate 2019
url https://doaj.org/article/4cfc0b4165e84f17b99eb2d432fcadb4
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