Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification

Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification

Tumour expression profiling is currently used for prognostic and predictive purposes without taking into account the intra patient heterogeneity. Here the authors show that cancer cell specific signatures overcome the tumour heterogeneity effect and result in better classification of colorectal canc...

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Bibliographic Details
Main Authors: Philip D. Dunne, Matthew Alderdice, Paul G. O'Reilly, Aideen C. Roddy, Amy M. B. McCorry, Susan Richman, Tim Maughan, Simon S. McDade, Patrick G. Johnston, Daniel B. Longley, Elaine Kay, Darragh G. McArt, Mark Lawler
Format: article
Language:EN
Published: Nature Portfolio 2017
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Science
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Online Access:https://doaj.org/article/4cfe33bfecaf449b9233c78e1aecfd67
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https://doaj.org/article/4cfe33bfecaf449b9233c78e1aecfd67

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