Prevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda

Abstract Individuals found at bars in slums have several risk factors for HIV and tuberculosis (TB). To determine the prevalence of HIV and TB among individuals found at bars in slums of Kampala, Uganda, we enrolled adults found at bars that provided written informed consent. Individuals with alcoho...

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Autores principales:	Joseph Baruch Baluku, Godwin Anguzu, Sylvia Nassozi, Febronius Babirye, Sharon Namiiro, Robert Buyungo, Mike Sempiira, Amir Wasswa, Rose Mulwana, Samuel Ntambi, William Worodria, Irene Andia-Biraro
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/4d07ba55fdf049549e6c5c67fe6982ff
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spelling	oai:doaj.org-article:4d07ba55fdf049549e6c5c67fe6982ff2021-12-02T18:50:57ZPrevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda10.1038/s41598-020-70472-62045-2322https://doaj.org/article/4d07ba55fdf049549e6c5c67fe6982ff2020-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-70472-6https://doaj.org/toc/2045-2322Abstract Individuals found at bars in slums have several risk factors for HIV and tuberculosis (TB). To determine the prevalence of HIV and TB among individuals found at bars in slums of Kampala, Uganda, we enrolled adults found at bars that provided written informed consent. Individuals with alcohol intoxication were excluded. We performed HIV testing using immunochromatographic antibody tests (Alere Determine HIV-1/2 and Chembio HIV 1/2 STAT-PAK). TB was confirmed using the Xpert MTB/RIF Ultra assay, performed on single spot sputum samples. We enrolled 272 participants from 42 bars in 5 slums. The prevalence of HIV and TB was 11.4% (95% CI 8.1–15.8) and 15 (95% CI 6–39) per 1,000 population respectively. Predictors of HIV were female sex (aOR 5.87, 95% CI 2.05–16.83), current cigarette smoking (aOR 3.23, 95% CI 1.02–10.26), history of TB treatment (aOR 10.19, 95% CI 3.17–32.82) and CAGE scores of 2–3 (aOR 3.90, 95% CI 1.11–13.70) and 4 (aOR 4.77, 95% CI 1.07–21.35). The prevalence of HIV and TB was twice and four times the national averages respectively. These findings highlight the need for concurrent programmatic screening for both HIV and TB among high risk populations in slums.Joseph Baruch BalukuGodwin AnguzuSylvia NassoziFebronius BabiryeSharon NamiiroRobert BuyungoMike SempiiraAmir WasswaRose MulwanaSamuel NtambiWilliam WorodriaIrene Andia-BiraroNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Joseph Baruch Baluku Godwin Anguzu Sylvia Nassozi Febronius Babirye Sharon Namiiro Robert Buyungo Mike Sempiira Amir Wasswa Rose Mulwana Samuel Ntambi William Worodria Irene Andia-Biraro Prevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda
description	Abstract Individuals found at bars in slums have several risk factors for HIV and tuberculosis (TB). To determine the prevalence of HIV and TB among individuals found at bars in slums of Kampala, Uganda, we enrolled adults found at bars that provided written informed consent. Individuals with alcohol intoxication were excluded. We performed HIV testing using immunochromatographic antibody tests (Alere Determine HIV-1/2 and Chembio HIV 1/2 STAT-PAK). TB was confirmed using the Xpert MTB/RIF Ultra assay, performed on single spot sputum samples. We enrolled 272 participants from 42 bars in 5 slums. The prevalence of HIV and TB was 11.4% (95% CI 8.1–15.8) and 15 (95% CI 6–39) per 1,000 population respectively. Predictors of HIV were female sex (aOR 5.87, 95% CI 2.05–16.83), current cigarette smoking (aOR 3.23, 95% CI 1.02–10.26), history of TB treatment (aOR 10.19, 95% CI 3.17–32.82) and CAGE scores of 2–3 (aOR 3.90, 95% CI 1.11–13.70) and 4 (aOR 4.77, 95% CI 1.07–21.35). The prevalence of HIV and TB was twice and four times the national averages respectively. These findings highlight the need for concurrent programmatic screening for both HIV and TB among high risk populations in slums.
format	article
author	Joseph Baruch Baluku Godwin Anguzu Sylvia Nassozi Febronius Babirye Sharon Namiiro Robert Buyungo Mike Sempiira Amir Wasswa Rose Mulwana Samuel Ntambi William Worodria Irene Andia-Biraro
author_facet	Joseph Baruch Baluku Godwin Anguzu Sylvia Nassozi Febronius Babirye Sharon Namiiro Robert Buyungo Mike Sempiira Amir Wasswa Rose Mulwana Samuel Ntambi William Worodria Irene Andia-Biraro
author_sort	Joseph Baruch Baluku
title	Prevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda
title_short	Prevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda
title_full	Prevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda
title_fullStr	Prevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda
title_full_unstemmed	Prevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda
title_sort	prevalence of hiv infection and bacteriologically confirmed tuberculosis among individuals found at bars in kampala slums, uganda
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/4d07ba55fdf049549e6c5c67fe6982ff
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Prevalence of HIV infection and bacteriologically confirmed tuberculosis among individuals found at bars in Kampala slums, Uganda

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