DIAGNOSTIC ACCURACY OF UTERINE ARTERY DOPPLER ULTRASOUND TO PREDICT PREECLAMPSIA IN PRIMIPAROUS FEMALES

Objective: To determine the diagnostic accuracy of Doppler ultrasonography during second trimester of pregnancy, to predict pre-eclampsia (PE) in primigravidas. Study Design: Cross sectional study. Place and Duration of Study: MCH unit-II, Pakistan Institute of Medical Sciences Islamabad, from...

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Autores principales:	Tayyaba Khan, Tahmina Yousaf, Saera Afghan, Komail Malik
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2019
Materias:	doppler ultrasonography Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/4d1cbe03b85d4ecca567fcb30ffb474c
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spelling	oai:doaj.org-article:4d1cbe03b85d4ecca567fcb30ffb474c2021-11-12T03:25:15ZDIAGNOSTIC ACCURACY OF UTERINE ARTERY DOPPLER ULTRASOUND TO PREDICT PREECLAMPSIA IN PRIMIPAROUS FEMALES0030-96482411-8842https://doaj.org/article/4d1cbe03b85d4ecca567fcb30ffb474c2019-06-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/3028/2266https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To determine the diagnostic accuracy of Doppler ultrasonography during second trimester of pregnancy, to predict pre-eclampsia (PE) in primigravidas. Study Design: Cross sectional study. Place and Duration of Study: MCH unit-II, Pakistan Institute of Medical Sciences Islamabad, from Apr 2015 to Oct 2015. Material and Method: A total of 170 females were recruited for the study. Doppler ultrasound examination of the uterine artery (UA) was performed, using a color Doppler system. Doppler parameters including resistance index (RI) was calculated by the software supplied within the Doppler equipment. Females were labeled as positive if RI >0.7 and were labeled as negative if RI <0.7. Then females were followed till third trimester and were carefully monitored for pre-eclampsia. The data was entered on the pre-designed proforma. Collected data was entered and analyzed through SPSS version 16. A 2x2 table was generated to calculate sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and diagnostic accuracy of Doppler ultrasonography, taking development of PE as gold standard. Results: The mean age of females was 27.46  4.67 years. The mean gestational age at time of recruitment was 20.95 ± 0.83 weeks. The mean height, weight and BMI of females were 1.66 ± 0.07meters, 72.85 ± 10.61kg and 26.63 ± 4.04kg/m2, respectively. There were 46 (27%) females who were obese while 124 (73%) females had normal BMI. At time of presentation of females, the RI on Doppler USG was >0.7 in 82 (48.2%) females while it was <0.7 in 88 (51.8%) females. There were 82 (48.2%) females who developed PE while 88 (51.8%) females did not develop PE at 20th week of gestation. Thus the calculated sensitivity, specificity, PPV and NPV of RI on Doppler USG were 85.4%, 86.4%, 85.4% and 86.4%. The overall diagnostic accuracy of RI was 85.9%. Conclusion: Doppler USG is accurate enough that in future we can rely on this tool for prediction of PE in primigravidas.Tayyaba KhanTahmina YousafSaera AfghanKomail MalikArmy Medical College Rawalpindiarticledoppler ultrasonographyMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 69, Iss 3, Pp 566-570 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	doppler ultrasonography Medicine R Medicine (General) R5-920
spellingShingle	doppler ultrasonography Medicine R Medicine (General) R5-920 Tayyaba Khan Tahmina Yousaf Saera Afghan Komail Malik DIAGNOSTIC ACCURACY OF UTERINE ARTERY DOPPLER ULTRASOUND TO PREDICT PREECLAMPSIA IN PRIMIPAROUS FEMALES
description	Objective: To determine the diagnostic accuracy of Doppler ultrasonography during second trimester of pregnancy, to predict pre-eclampsia (PE) in primigravidas. Study Design: Cross sectional study. Place and Duration of Study: MCH unit-II, Pakistan Institute of Medical Sciences Islamabad, from Apr 2015 to Oct 2015. Material and Method: A total of 170 females were recruited for the study. Doppler ultrasound examination of the uterine artery (UA) was performed, using a color Doppler system. Doppler parameters including resistance index (RI) was calculated by the software supplied within the Doppler equipment. Females were labeled as positive if RI >0.7 and were labeled as negative if RI <0.7. Then females were followed till third trimester and were carefully monitored for pre-eclampsia. The data was entered on the pre-designed proforma. Collected data was entered and analyzed through SPSS version 16. A 2x2 table was generated to calculate sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and diagnostic accuracy of Doppler ultrasonography, taking development of PE as gold standard. Results: The mean age of females was 27.46  4.67 years. The mean gestational age at time of recruitment was 20.95 ± 0.83 weeks. The mean height, weight and BMI of females were 1.66 ± 0.07meters, 72.85 ± 10.61kg and 26.63 ± 4.04kg/m2, respectively. There were 46 (27%) females who were obese while 124 (73%) females had normal BMI. At time of presentation of females, the RI on Doppler USG was >0.7 in 82 (48.2%) females while it was <0.7 in 88 (51.8%) females. There were 82 (48.2%) females who developed PE while 88 (51.8%) females did not develop PE at 20th week of gestation. Thus the calculated sensitivity, specificity, PPV and NPV of RI on Doppler USG were 85.4%, 86.4%, 85.4% and 86.4%. The overall diagnostic accuracy of RI was 85.9%. Conclusion: Doppler USG is accurate enough that in future we can rely on this tool for prediction of PE in primigravidas.
format	article
author	Tayyaba Khan Tahmina Yousaf Saera Afghan Komail Malik
author_facet	Tayyaba Khan Tahmina Yousaf Saera Afghan Komail Malik
author_sort	Tayyaba Khan
title	DIAGNOSTIC ACCURACY OF UTERINE ARTERY DOPPLER ULTRASOUND TO PREDICT PREECLAMPSIA IN PRIMIPAROUS FEMALES
title_short	DIAGNOSTIC ACCURACY OF UTERINE ARTERY DOPPLER ULTRASOUND TO PREDICT PREECLAMPSIA IN PRIMIPAROUS FEMALES
title_full	DIAGNOSTIC ACCURACY OF UTERINE ARTERY DOPPLER ULTRASOUND TO PREDICT PREECLAMPSIA IN PRIMIPAROUS FEMALES
title_fullStr	DIAGNOSTIC ACCURACY OF UTERINE ARTERY DOPPLER ULTRASOUND TO PREDICT PREECLAMPSIA IN PRIMIPAROUS FEMALES
title_full_unstemmed	DIAGNOSTIC ACCURACY OF UTERINE ARTERY DOPPLER ULTRASOUND TO PREDICT PREECLAMPSIA IN PRIMIPAROUS FEMALES
title_sort	diagnostic accuracy of uterine artery doppler ultrasound to predict preeclampsia in primiparous females
publisher	Army Medical College Rawalpindi
publishDate	2019
url	https://doaj.org/article/4d1cbe03b85d4ecca567fcb30ffb474c
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DIAGNOSTIC ACCURACY OF UTERINE ARTERY DOPPLER ULTRASOUND TO PREDICT PREECLAMPSIA IN PRIMIPAROUS FEMALES

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