DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS

Abstract. We have observed 128 patients with non-nosocomial pneumonias. Bacterial microflora was isolated in 22.6 per cent of entire group. 17 per cent of the samples were seropositive for Mycoplasma pneumoniae, along with detectable DNA specific for this causal agent. In 25 per cent of the patients...

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Autores principales:	T. I. Dolgikh, V. I. Sovalkin, I. V. Menshchikova
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	pneumonia m. pneumoniae cytokines immunity tnfα il-8 il-6 Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/4d39a71439684691a2aacd00e58d8969
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spelling	oai:doaj.org-article:4d39a71439684691a2aacd00e58d89692021-11-18T08:03:39ZDIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS1563-06252313-741X10.15789/1563-0625-2007-4-5-519-522https://doaj.org/article/4d39a71439684691a2aacd00e58d89692014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/233https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. We have observed 128 patients with non-nosocomial pneumonias. Bacterial microflora was isolated in 22.6 per cent of entire group. 17 per cent of the samples were seropositive for Mycoplasma pneumoniae, along with detectable DNA specific for this causal agent. In 25 per cent of the patients, isolation of bacterial microflora was associated with positive antibody titers to Mycoplasma pneumoniae. Serum contents of cytokines (TNFα, IL-8, IL-6) have been studied in the patients. A positive correlation was found between increased cytokine levels and severity of the disease.T. I. DolgikhV. I. SovalkinI. V. MenshchikovaSPb RAACIarticlepneumoniam. pneumoniaecytokinesimmunitytnfαil-8il-6Immunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 9, Iss 4-5, Pp 519-522 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	pneumonia m. pneumoniae cytokines immunity tnfα il-8 il-6 Immunologic diseases. Allergy RC581-607
spellingShingle	pneumonia m. pneumoniae cytokines immunity tnfα il-8 il-6 Immunologic diseases. Allergy RC581-607 T. I. Dolgikh V. I. Sovalkin I. V. Menshchikova DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS
description	Abstract. We have observed 128 patients with non-nosocomial pneumonias. Bacterial microflora was isolated in 22.6 per cent of entire group. 17 per cent of the samples were seropositive for Mycoplasma pneumoniae, along with detectable DNA specific for this causal agent. In 25 per cent of the patients, isolation of bacterial microflora was associated with positive antibody titers to Mycoplasma pneumoniae. Serum contents of cytokines (TNFα, IL-8, IL-6) have been studied in the patients. A positive correlation was found between increased cytokine levels and severity of the disease.
format	article
author	T. I. Dolgikh V. I. Sovalkin I. V. Menshchikova
author_facet	T. I. Dolgikh V. I. Sovalkin I. V. Menshchikova
author_sort	T. I. Dolgikh
title	DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS
title_short	DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS
title_full	DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS
title_fullStr	DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS
title_full_unstemmed	DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS
title_sort	diagnostic and predictive value of tnf α, il-8 and il-6 assays in the patients with mycoplasma-associated pneumonias
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/4d39a71439684691a2aacd00e58d8969
work_keys_str_mv	AT tidolgikh diagnosticandpredictivevalueoftnfail8andil6assaysinthepatientswithmycoplasmaassociatedpneumonias AT visovalkin diagnosticandpredictivevalueoftnfail8andil6assaysinthepatientswithmycoplasmaassociatedpneumonias AT ivmenshchikova diagnosticandpredictivevalueoftnfail8andil6assaysinthepatientswithmycoplasmaassociatedpneumonias
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DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS

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