Mapping the mutual information network of enzymatic families in the protein structure to unveil functional features.
Amino acids committed to a particular function correlate tightly along evolution and tend to form clusters in the 3D structure of the protein. Consequently, a protein can be seen as a network of co-evolving clusters of residues. The goal of this work is two-fold: first, we have combined mutual infor...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2012
|
| Subjects: | |
| Online Access: | https://doaj.org/article/4d3c88af5d6e46cf9c3da22ca133298f |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|