Production of zosteric acid and other sulfated phenolic biochemicals in microbial cell factories
Toxicity and limited solubility inhibits the biological production of many organic compounds. Here the authors metabolically engineer sulfate uptake and activation in order to produce sulfate esters of phenolic compounds, such as zosteric acid, thereby addressing these issues.
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Nature Portfolio
2019
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oai:doaj.org-article:4d40893c73e04afca88245dc6f05483d2021-12-02T16:57:50ZProduction of zosteric acid and other sulfated phenolic biochemicals in microbial cell factories10.1038/s41467-019-12022-x2041-1723https://doaj.org/article/4d40893c73e04afca88245dc6f05483d2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12022-xhttps://doaj.org/toc/2041-1723Toxicity and limited solubility inhibits the biological production of many organic compounds. Here the authors metabolically engineer sulfate uptake and activation in order to produce sulfate esters of phenolic compounds, such as zosteric acid, thereby addressing these issues.Christian Bille JendresenAlex Toftgaard NielsenNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019) |
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Science Q |
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Science Q Christian Bille Jendresen Alex Toftgaard Nielsen Production of zosteric acid and other sulfated phenolic biochemicals in microbial cell factories |
description |
Toxicity and limited solubility inhibits the biological production of many organic compounds. Here the authors metabolically engineer sulfate uptake and activation in order to produce sulfate esters of phenolic compounds, such as zosteric acid, thereby addressing these issues. |
format |
article |
author |
Christian Bille Jendresen Alex Toftgaard Nielsen |
author_facet |
Christian Bille Jendresen Alex Toftgaard Nielsen |
author_sort |
Christian Bille Jendresen |
title |
Production of zosteric acid and other sulfated phenolic biochemicals in microbial cell factories |
title_short |
Production of zosteric acid and other sulfated phenolic biochemicals in microbial cell factories |
title_full |
Production of zosteric acid and other sulfated phenolic biochemicals in microbial cell factories |
title_fullStr |
Production of zosteric acid and other sulfated phenolic biochemicals in microbial cell factories |
title_full_unstemmed |
Production of zosteric acid and other sulfated phenolic biochemicals in microbial cell factories |
title_sort |
production of zosteric acid and other sulfated phenolic biochemicals in microbial cell factories |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/4d40893c73e04afca88245dc6f05483d |
work_keys_str_mv |
AT christianbillejendresen productionofzostericacidandothersulfatedphenolicbiochemicalsinmicrobialcellfactories AT alextoftgaardnielsen productionofzostericacidandothersulfatedphenolicbiochemicalsinmicrobialcellfactories |
_version_ |
1718382444406636544 |