iRGD synergizes with PD-1 knockout immunotherapy by enhancing lymphocyte infiltration in gastric cancer
The therapeutic efficacy of adoptive T cell transfer is limited by their ability to infiltrate solid tumours. Here, the authors show that loading the tumor penetrating cyclic peptide iRGD on the cell surface of T cells enhances their ability to penetrate the tumour, resulting in enhanced efficacy in...
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Autores principales: | Naiqing Ding, Zhengyun Zou, Huizi Sha, Shu Su, Hanqing Qian, Fanyan Meng, Fangjun Chen, Shiyao Du, Shujuan Zhou, Hong Chen, Lianru Zhang, Ju Yang, Jia Wei, Baorui Liu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/4d424ce982544f98bbf28d7feda3ba49 |
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