PD-1 regulates neural damage in oligodendroglia-induced inflammation.

PD-1 regulates neural damage in oligodendroglia-induced inflammation.

We investigated the impact of immune regulatory mechanisms involved in the modulation of the recently presented, CD8+ lymphocyte mediated immune response in a mouse model of oligodendropathy-induced inflammation (PLPtg-mutants). The focus was on the role of the co-inhibitory molecule PD-1, a CD28-re...

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Autores principales: Antje Kroner, Nicholas Schwab, Chi Wang Ip, Christoph Leder, Klaus-Armin Nave, Mathias Mäurer, Heinz Wiendl, Rudolf Martini
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/4d4aa06cbc694aa491852a44bf65b1d0
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