An optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits
Mechanisms of neural processing can only be understood by revealing patterns of connectivity among the cellular components of the circuit. Here the authors report a new genetic toolbox, ‘Optobow’, which enables simultaneous optogenetic activation of single neurons in zebrafish and measuring the acti...
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Nature Portfolio
2017
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oai:doaj.org-article:4d54732f5dfe483797ba4197fca988fd2021-12-02T13:23:47ZAn optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits10.1038/s41467-017-00160-z2041-1723https://doaj.org/article/4d54732f5dfe483797ba4197fca988fd2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00160-zhttps://doaj.org/toc/2041-1723Mechanisms of neural processing can only be understood by revealing patterns of connectivity among the cellular components of the circuit. Here the authors report a new genetic toolbox, ‘Optobow’, which enables simultaneous optogenetic activation of single neurons in zebrafish and measuring the activity of downstream neurons in the network.Dominique FörsterMarco Dal MaschioEva LaurellHerwig BaierNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017) |
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Science Q Dominique Förster Marco Dal Maschio Eva Laurell Herwig Baier An optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits |
description |
Mechanisms of neural processing can only be understood by revealing patterns of connectivity among the cellular components of the circuit. Here the authors report a new genetic toolbox, ‘Optobow’, which enables simultaneous optogenetic activation of single neurons in zebrafish and measuring the activity of downstream neurons in the network. |
format |
article |
author |
Dominique Förster Marco Dal Maschio Eva Laurell Herwig Baier |
author_facet |
Dominique Förster Marco Dal Maschio Eva Laurell Herwig Baier |
author_sort |
Dominique Förster |
title |
An optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits |
title_short |
An optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits |
title_full |
An optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits |
title_fullStr |
An optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits |
title_full_unstemmed |
An optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits |
title_sort |
optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/4d54732f5dfe483797ba4197fca988fd |
work_keys_str_mv |
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