An optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits

Mechanisms of neural processing can only be understood by revealing patterns of connectivity among the cellular components of the circuit. Here the authors report a new genetic toolbox, ‘Optobow’, which enables simultaneous optogenetic activation of single neurons in zebrafish and measuring the acti...

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Autores principales: Dominique Förster, Marco Dal Maschio, Eva Laurell, Herwig Baier
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/4d54732f5dfe483797ba4197fca988fd
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spelling oai:doaj.org-article:4d54732f5dfe483797ba4197fca988fd2021-12-02T13:23:47ZAn optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits10.1038/s41467-017-00160-z2041-1723https://doaj.org/article/4d54732f5dfe483797ba4197fca988fd2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00160-zhttps://doaj.org/toc/2041-1723Mechanisms of neural processing can only be understood by revealing patterns of connectivity among the cellular components of the circuit. Here the authors report a new genetic toolbox, ‘Optobow’, which enables simultaneous optogenetic activation of single neurons in zebrafish and measuring the activity of downstream neurons in the network.Dominique FörsterMarco Dal MaschioEva LaurellHerwig BaierNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dominique Förster
Marco Dal Maschio
Eva Laurell
Herwig Baier
An optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits
description Mechanisms of neural processing can only be understood by revealing patterns of connectivity among the cellular components of the circuit. Here the authors report a new genetic toolbox, ‘Optobow’, which enables simultaneous optogenetic activation of single neurons in zebrafish and measuring the activity of downstream neurons in the network.
format article
author Dominique Förster
Marco Dal Maschio
Eva Laurell
Herwig Baier
author_facet Dominique Förster
Marco Dal Maschio
Eva Laurell
Herwig Baier
author_sort Dominique Förster
title An optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits
title_short An optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits
title_full An optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits
title_fullStr An optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits
title_full_unstemmed An optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits
title_sort optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/4d54732f5dfe483797ba4197fca988fd
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