Dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories
Flexible fear-related responses may be advantageous in adolescence. Here the authors use microprisms to image prefrontal cortical spine maturation across development and report that plasticity in adolescent fear extinction responses is associated with dynamic reorganization in the amygdalahippocampa...
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Nature Portfolio
2016
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oai:doaj.org-article:4d58c976b94049eb80787cf1cc8bf9b22021-12-02T17:31:19ZDynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories10.1038/ncomms114752041-1723https://doaj.org/article/4d58c976b94049eb80787cf1cc8bf9b22016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11475https://doaj.org/toc/2041-1723Flexible fear-related responses may be advantageous in adolescence. Here the authors use microprisms to image prefrontal cortical spine maturation across development and report that plasticity in adolescent fear extinction responses is associated with dynamic reorganization in the amygdalahippocampal-PFC circuit.Siobhan S. PattwellConor ListonDeqiang JingIpe NinanRui R. YangJonathan WitztumMitchell H. MurdockIva DinchevaKevin G. BathB. J. CaseyKarl DeisserothFrancis S. LeeNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016) |
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Science Q Siobhan S. Pattwell Conor Liston Deqiang Jing Ipe Ninan Rui R. Yang Jonathan Witztum Mitchell H. Murdock Iva Dincheva Kevin G. Bath B. J. Casey Karl Deisseroth Francis S. Lee Dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories |
description |
Flexible fear-related responses may be advantageous in adolescence. Here the authors use microprisms to image prefrontal cortical spine maturation across development and report that plasticity in adolescent fear extinction responses is associated with dynamic reorganization in the amygdalahippocampal-PFC circuit. |
format |
article |
author |
Siobhan S. Pattwell Conor Liston Deqiang Jing Ipe Ninan Rui R. Yang Jonathan Witztum Mitchell H. Murdock Iva Dincheva Kevin G. Bath B. J. Casey Karl Deisseroth Francis S. Lee |
author_facet |
Siobhan S. Pattwell Conor Liston Deqiang Jing Ipe Ninan Rui R. Yang Jonathan Witztum Mitchell H. Murdock Iva Dincheva Kevin G. Bath B. J. Casey Karl Deisseroth Francis S. Lee |
author_sort |
Siobhan S. Pattwell |
title |
Dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories |
title_short |
Dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories |
title_full |
Dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories |
title_fullStr |
Dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories |
title_full_unstemmed |
Dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories |
title_sort |
dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/4d58c976b94049eb80787cf1cc8bf9b2 |
work_keys_str_mv |
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1718380610753396736 |