Dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories

Flexible fear-related responses may be advantageous in adolescence. Here the authors use microprisms to image prefrontal cortical spine maturation across development and report that plasticity in adolescent fear extinction responses is associated with dynamic reorganization in the amygdalahippocampa...

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Autores principales: Siobhan S. Pattwell, Conor Liston, Deqiang Jing, Ipe Ninan, Rui R. Yang, Jonathan Witztum, Mitchell H. Murdock, Iva Dincheva, Kevin G. Bath, B. J. Casey, Karl Deisseroth, Francis S. Lee
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/4d58c976b94049eb80787cf1cc8bf9b2
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spelling oai:doaj.org-article:4d58c976b94049eb80787cf1cc8bf9b22021-12-02T17:31:19ZDynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories10.1038/ncomms114752041-1723https://doaj.org/article/4d58c976b94049eb80787cf1cc8bf9b22016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11475https://doaj.org/toc/2041-1723Flexible fear-related responses may be advantageous in adolescence. Here the authors use microprisms to image prefrontal cortical spine maturation across development and report that plasticity in adolescent fear extinction responses is associated with dynamic reorganization in the amygdalahippocampal-PFC circuit.Siobhan S. PattwellConor ListonDeqiang JingIpe NinanRui R. YangJonathan WitztumMitchell H. MurdockIva DinchevaKevin G. BathB. J. CaseyKarl DeisserothFrancis S. LeeNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Siobhan S. Pattwell
Conor Liston
Deqiang Jing
Ipe Ninan
Rui R. Yang
Jonathan Witztum
Mitchell H. Murdock
Iva Dincheva
Kevin G. Bath
B. J. Casey
Karl Deisseroth
Francis S. Lee
Dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories
description Flexible fear-related responses may be advantageous in adolescence. Here the authors use microprisms to image prefrontal cortical spine maturation across development and report that plasticity in adolescent fear extinction responses is associated with dynamic reorganization in the amygdalahippocampal-PFC circuit.
format article
author Siobhan S. Pattwell
Conor Liston
Deqiang Jing
Ipe Ninan
Rui R. Yang
Jonathan Witztum
Mitchell H. Murdock
Iva Dincheva
Kevin G. Bath
B. J. Casey
Karl Deisseroth
Francis S. Lee
author_facet Siobhan S. Pattwell
Conor Liston
Deqiang Jing
Ipe Ninan
Rui R. Yang
Jonathan Witztum
Mitchell H. Murdock
Iva Dincheva
Kevin G. Bath
B. J. Casey
Karl Deisseroth
Francis S. Lee
author_sort Siobhan S. Pattwell
title Dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories
title_short Dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories
title_full Dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories
title_fullStr Dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories
title_full_unstemmed Dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories
title_sort dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/4d58c976b94049eb80787cf1cc8bf9b2
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