A scalable workflow to characterize the human exposome

Humans are exposed to millions of chemicals but mass spectrometry (MS)-based targeted biomonitoring assays are usually limited to a few hundred known hazards. Here, the authors develop a workflow for MS-based untargeted exposome profiling of known and unidentified environmental chemicals.

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Autores principales: Xin Hu, Douglas I. Walker, Yongliang Liang, Matthew Ryan Smith, Michael L. Orr, Brian D. Juran, Chunyu Ma, Karan Uppal, Michael Koval, Greg S. Martin, David C. Neujahr, Carmen J. Marsit, Young-Mi Go, Kurt D. Pennell, Gary W. Miller, Konstantinos N. Lazaridis, Dean P. Jones
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4d62c49b878b4caf97797da50f1ea5a1
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spelling oai:doaj.org-article:4d62c49b878b4caf97797da50f1ea5a12021-12-02T18:14:09ZA scalable workflow to characterize the human exposome10.1038/s41467-021-25840-92041-1723https://doaj.org/article/4d62c49b878b4caf97797da50f1ea5a12021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25840-9https://doaj.org/toc/2041-1723Humans are exposed to millions of chemicals but mass spectrometry (MS)-based targeted biomonitoring assays are usually limited to a few hundred known hazards. Here, the authors develop a workflow for MS-based untargeted exposome profiling of known and unidentified environmental chemicals.Xin HuDouglas I. WalkerYongliang LiangMatthew Ryan SmithMichael L. OrrBrian D. JuranChunyu MaKaran UppalMichael KovalGreg S. MartinDavid C. NeujahrCarmen J. MarsitYoung-Mi GoKurt D. PennellGary W. MillerKonstantinos N. LazaridisDean P. JonesNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xin Hu
Douglas I. Walker
Yongliang Liang
Matthew Ryan Smith
Michael L. Orr
Brian D. Juran
Chunyu Ma
Karan Uppal
Michael Koval
Greg S. Martin
David C. Neujahr
Carmen J. Marsit
Young-Mi Go
Kurt D. Pennell
Gary W. Miller
Konstantinos N. Lazaridis
Dean P. Jones
A scalable workflow to characterize the human exposome
description Humans are exposed to millions of chemicals but mass spectrometry (MS)-based targeted biomonitoring assays are usually limited to a few hundred known hazards. Here, the authors develop a workflow for MS-based untargeted exposome profiling of known and unidentified environmental chemicals.
format article
author Xin Hu
Douglas I. Walker
Yongliang Liang
Matthew Ryan Smith
Michael L. Orr
Brian D. Juran
Chunyu Ma
Karan Uppal
Michael Koval
Greg S. Martin
David C. Neujahr
Carmen J. Marsit
Young-Mi Go
Kurt D. Pennell
Gary W. Miller
Konstantinos N. Lazaridis
Dean P. Jones
author_facet Xin Hu
Douglas I. Walker
Yongliang Liang
Matthew Ryan Smith
Michael L. Orr
Brian D. Juran
Chunyu Ma
Karan Uppal
Michael Koval
Greg S. Martin
David C. Neujahr
Carmen J. Marsit
Young-Mi Go
Kurt D. Pennell
Gary W. Miller
Konstantinos N. Lazaridis
Dean P. Jones
author_sort Xin Hu
title A scalable workflow to characterize the human exposome
title_short A scalable workflow to characterize the human exposome
title_full A scalable workflow to characterize the human exposome
title_fullStr A scalable workflow to characterize the human exposome
title_full_unstemmed A scalable workflow to characterize the human exposome
title_sort scalable workflow to characterize the human exposome
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/4d62c49b878b4caf97797da50f1ea5a1
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