Initiating an epilepsy surgery program with limited resources in Indonesia

Abstract To share the experiences of organizing the epilepsy surgery program in Indonesia. This study was divided into two periods based on the presurgical evaluation method: the first period (1999–2004), when interictal electroencephalogram (EEG) and magnetic resonance imaging (MRI) were used mainl...

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Autores principales:	Muhamad Thohar Arifin, Ryosuke Hanaya, Yuriz Bakhtiar, Aris Catur Bintoro, Koji Iida, Kaoru Kurisu, Kazunori Arita, Jacob Bunyamin, Rofat Askoro, Surya Pratama Brilliantika, Novita Ikbar Khairunnisa, Zainal Muttaqin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/4d6ab90344754580a7e1eae8db1ba352
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spelling	oai:doaj.org-article:4d6ab90344754580a7e1eae8db1ba3522021-12-02T15:54:13ZInitiating an epilepsy surgery program with limited resources in Indonesia10.1038/s41598-021-84404-52045-2322https://doaj.org/article/4d6ab90344754580a7e1eae8db1ba3522021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-84404-5https://doaj.org/toc/2045-2322Abstract To share the experiences of organizing the epilepsy surgery program in Indonesia. This study was divided into two periods based on the presurgical evaluation method: the first period (1999–2004), when interictal electroencephalogram (EEG) and magnetic resonance imaging (MRI) were used mainly for confirmation, and the second period (2005–2017), when long-term non-invasive and invasive video-EEG was involved in the evaluation. Long-term outcomes were recorded up to December 2019 based on the Engel scale. All 65 surgical recruits in the first period possessed temporal lobe epilepsy (TLE), while 524 patients were treated in the second period. In the first period, 76.8%, 16.1%, and 7.1% of patients with TLE achieved Classes I, II, and III, respectively, and in the second period, 89.4%, 5.5%, and 4.9% achieved Classes I, II, and III, respectively, alongside Class IV, at 0.3%. The overall median survival times for patients with focal impaired awareness seizures (FIAS), focal to bilateral tonic–clonic seizures and generalized tonic–clonic seizures were 9, 11 and 11 years (95% CI: 8.170–9.830, 10.170–11.830, and 7.265–14.735), respectively, with p = 0.04. The utilization of stringent and selective criteria to reserve surgeries is important for a successful epilepsy program with limited resources.Muhamad Thohar ArifinRyosuke HanayaYuriz BakhtiarAris Catur BintoroKoji IidaKaoru KurisuKazunori AritaJacob BunyaminRofat AskoroSurya Pratama BrilliantikaNovita Ikbar KhairunnisaZainal MuttaqinNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Muhamad Thohar Arifin Ryosuke Hanaya Yuriz Bakhtiar Aris Catur Bintoro Koji Iida Kaoru Kurisu Kazunori Arita Jacob Bunyamin Rofat Askoro Surya Pratama Brilliantika Novita Ikbar Khairunnisa Zainal Muttaqin Initiating an epilepsy surgery program with limited resources in Indonesia
description	Abstract To share the experiences of organizing the epilepsy surgery program in Indonesia. This study was divided into two periods based on the presurgical evaluation method: the first period (1999–2004), when interictal electroencephalogram (EEG) and magnetic resonance imaging (MRI) were used mainly for confirmation, and the second period (2005–2017), when long-term non-invasive and invasive video-EEG was involved in the evaluation. Long-term outcomes were recorded up to December 2019 based on the Engel scale. All 65 surgical recruits in the first period possessed temporal lobe epilepsy (TLE), while 524 patients were treated in the second period. In the first period, 76.8%, 16.1%, and 7.1% of patients with TLE achieved Classes I, II, and III, respectively, and in the second period, 89.4%, 5.5%, and 4.9% achieved Classes I, II, and III, respectively, alongside Class IV, at 0.3%. The overall median survival times for patients with focal impaired awareness seizures (FIAS), focal to bilateral tonic–clonic seizures and generalized tonic–clonic seizures were 9, 11 and 11 years (95% CI: 8.170–9.830, 10.170–11.830, and 7.265–14.735), respectively, with p = 0.04. The utilization of stringent and selective criteria to reserve surgeries is important for a successful epilepsy program with limited resources.
format	article
author	Muhamad Thohar Arifin Ryosuke Hanaya Yuriz Bakhtiar Aris Catur Bintoro Koji Iida Kaoru Kurisu Kazunori Arita Jacob Bunyamin Rofat Askoro Surya Pratama Brilliantika Novita Ikbar Khairunnisa Zainal Muttaqin
author_facet	Muhamad Thohar Arifin Ryosuke Hanaya Yuriz Bakhtiar Aris Catur Bintoro Koji Iida Kaoru Kurisu Kazunori Arita Jacob Bunyamin Rofat Askoro Surya Pratama Brilliantika Novita Ikbar Khairunnisa Zainal Muttaqin
author_sort	Muhamad Thohar Arifin
title	Initiating an epilepsy surgery program with limited resources in Indonesia
title_short	Initiating an epilepsy surgery program with limited resources in Indonesia
title_full	Initiating an epilepsy surgery program with limited resources in Indonesia
title_fullStr	Initiating an epilepsy surgery program with limited resources in Indonesia
title_full_unstemmed	Initiating an epilepsy surgery program with limited resources in Indonesia
title_sort	initiating an epilepsy surgery program with limited resources in indonesia
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4d6ab90344754580a7e1eae8db1ba352
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Initiating an epilepsy surgery program with limited resources in Indonesia

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