HIV-1 Escape from Small-Molecule Antagonism of Vif
ABSTRACT The HIV-1 accessory protein Vif, which counteracts the antiviral action of the DNA-editing cytidine deaminase APOBEC3G (A3G), is an attractive and yet unexploited therapeutic target. Vif reduces the virion incorporation of A3G by targeting the restriction factor for proteasomal degradation...
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| Main Authors: | , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2019
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| Subjects: | |
| Online Access: | https://doaj.org/article/4d8741ca218e4772905c111bd892ffb2 |
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