Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements

Essig et al used a combination of behavior, optogenetics, neural recordings and modelling to directly examine the contribution of GABAergic superior colliculus neurons to the selection of opposing spatial targets. They demonstrated that these neurons do not locally suppress premotor output, suggesti...

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Autores principales:	Jaclyn Essig, Joshua B. Hunt, Gidon Felsen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/4d9635fae3884e5b8809b8c63d6020a3
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spelling	oai:doaj.org-article:4d9635fae3884e5b8809b8c63d6020a32021-12-02T17:47:03ZInhibitory neurons in the superior colliculus mediate selection of spatially-directed movements10.1038/s42003-021-02248-12399-3642https://doaj.org/article/4d9635fae3884e5b8809b8c63d6020a32021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02248-1https://doaj.org/toc/2399-3642Essig et al used a combination of behavior, optogenetics, neural recordings and modelling to directly examine the contribution of GABAergic superior colliculus neurons to the selection of opposing spatial targets. They demonstrated that these neurons do not locally suppress premotor output, suggesting that functional long-range inhibition instead plays a dominant role in spatial choice.Jaclyn EssigJoshua B. HuntGidon FelsenNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Jaclyn Essig Joshua B. Hunt Gidon Felsen Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements
description	Essig et al used a combination of behavior, optogenetics, neural recordings and modelling to directly examine the contribution of GABAergic superior colliculus neurons to the selection of opposing spatial targets. They demonstrated that these neurons do not locally suppress premotor output, suggesting that functional long-range inhibition instead plays a dominant role in spatial choice.
format	article
author	Jaclyn Essig Joshua B. Hunt Gidon Felsen
author_facet	Jaclyn Essig Joshua B. Hunt Gidon Felsen
author_sort	Jaclyn Essig
title	Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements
title_short	Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements
title_full	Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements
title_fullStr	Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements
title_full_unstemmed	Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements
title_sort	inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4d9635fae3884e5b8809b8c63d6020a3
work_keys_str_mv	AT jaclynessig inhibitoryneuronsinthesuperiorcolliculusmediateselectionofspatiallydirectedmovements AT joshuabhunt inhibitoryneuronsinthesuperiorcolliculusmediateselectionofspatiallydirectedmovements AT gidonfelsen inhibitoryneuronsinthesuperiorcolliculusmediateselectionofspatiallydirectedmovements
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Inhibitory neurons in the superior colliculus mediate selection of spatially-directed movements

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