The function and three-dimensional structure of a thromboxane A2/cysteinyl leukotriene-binding protein from the saliva of a mosquito vector of the malaria parasite.

The highly expressed D7 protein family of mosquito saliva has previously been shown to act as an anti-inflammatory mediator by binding host biogenic amines and cysteinyl leukotrienes (CysLTs). In this study we demonstrate that AnSt-D7L1, a two-domain member of this group from Anopheles stephensi, re...

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Main Authors: Patricia H Alvarenga, Ivo M B Francischetti, Eric Calvo, Anderson Sá-Nunes, José M C Ribeiro, John F Andersen
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2010
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Online Access:https://doaj.org/article/4d9bc8d7659a496db0d15d89586da94d
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