The serotonin transporter gene and female personality variation in a free-living passerine

Abstract Quantifying variation in behaviour-related genes provides insight into the evolutionary potential of repeatable among-individual variation in behaviour (i.e. personality). Yet, individuals typically also plastically adjust their behaviour in response to environmental conditions and/or age,...

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Autores principales:	Bert Thys, Andrea S. Grunst, Nicky Staes, Rianne Pinxten, Marcel Eens, Melissa L. Grunst
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/4da46b0b5df14b83b94941ecf583eea7
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spelling	oai:doaj.org-article:4da46b0b5df14b83b94941ecf583eea72021-12-02T17:32:59ZThe serotonin transporter gene and female personality variation in a free-living passerine10.1038/s41598-021-88225-42045-2322https://doaj.org/article/4da46b0b5df14b83b94941ecf583eea72021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-88225-4https://doaj.org/toc/2045-2322Abstract Quantifying variation in behaviour-related genes provides insight into the evolutionary potential of repeatable among-individual variation in behaviour (i.e. personality). Yet, individuals typically also plastically adjust their behaviour in response to environmental conditions and/or age, thereby complicating the detection of genotype–phenotype associations. Here, using a population of free-living great tits (Parus major), we assessed the association between single nucleotide polymorphisms (SNPs) in the serotonin transporter gene (SERT) and two repeatable behavioural traits, i.e. female-female aggression and female hissing behaviour. For female-female aggression, a trait showing age-related plasticity, we found no evidence for associations with SERT SNPs, even when assessing potential age-dependent effects of SERT genotype on aggression. We also found no strong support for associations between SERT SNPs and hissing behaviour, yet we identified two synonymous polymorphisms (exon 13 SNP66 and exon 12 SNP144) of particular interest, each explaining about 1.3% of the total variation in hissing behaviour. Overall, our results contribute to the general understanding of the biological underpinning of complex behavioural traits and will facilitate further (meta-analytic) research on behaviour-related genes. Moreover, we emphasize that future molecular genetic studies should consider age-dependent genotype–phenotype associations for behavioural trait (co)variation, as this will vastly improve our understanding of the proximate causes and ultimate consequences of personality variation in natural populations.Bert ThysAndrea S. GrunstNicky StaesRianne PinxtenMarcel EensMelissa L. GrunstNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Bert Thys Andrea S. Grunst Nicky Staes Rianne Pinxten Marcel Eens Melissa L. Grunst The serotonin transporter gene and female personality variation in a free-living passerine
description	Abstract Quantifying variation in behaviour-related genes provides insight into the evolutionary potential of repeatable among-individual variation in behaviour (i.e. personality). Yet, individuals typically also plastically adjust their behaviour in response to environmental conditions and/or age, thereby complicating the detection of genotype–phenotype associations. Here, using a population of free-living great tits (Parus major), we assessed the association between single nucleotide polymorphisms (SNPs) in the serotonin transporter gene (SERT) and two repeatable behavioural traits, i.e. female-female aggression and female hissing behaviour. For female-female aggression, a trait showing age-related plasticity, we found no evidence for associations with SERT SNPs, even when assessing potential age-dependent effects of SERT genotype on aggression. We also found no strong support for associations between SERT SNPs and hissing behaviour, yet we identified two synonymous polymorphisms (exon 13 SNP66 and exon 12 SNP144) of particular interest, each explaining about 1.3% of the total variation in hissing behaviour. Overall, our results contribute to the general understanding of the biological underpinning of complex behavioural traits and will facilitate further (meta-analytic) research on behaviour-related genes. Moreover, we emphasize that future molecular genetic studies should consider age-dependent genotype–phenotype associations for behavioural trait (co)variation, as this will vastly improve our understanding of the proximate causes and ultimate consequences of personality variation in natural populations.
format	article
author	Bert Thys Andrea S. Grunst Nicky Staes Rianne Pinxten Marcel Eens Melissa L. Grunst
author_facet	Bert Thys Andrea S. Grunst Nicky Staes Rianne Pinxten Marcel Eens Melissa L. Grunst
author_sort	Bert Thys
title	The serotonin transporter gene and female personality variation in a free-living passerine
title_short	The serotonin transporter gene and female personality variation in a free-living passerine
title_full	The serotonin transporter gene and female personality variation in a free-living passerine
title_fullStr	The serotonin transporter gene and female personality variation in a free-living passerine
title_full_unstemmed	The serotonin transporter gene and female personality variation in a free-living passerine
title_sort	serotonin transporter gene and female personality variation in a free-living passerine
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4da46b0b5df14b83b94941ecf583eea7
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The serotonin transporter gene and female personality variation in a free-living passerine

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