Trace Elements and Vitamin D in Gestational Diabetes

Gestational diabetes mellitus (GDM), one of the most common pregnancy complications, is defined as glucose intolerance with onset or first recognition during pregnancy. Its prevalence varies worldwide in dependence on characteristics of the underlying population and applied diagnostic criteria. The...

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Autores principales: Genova Mariana, Atanasova B., Ivanova I., Todorova K., Svinarov D.
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Lenguaje:EN
Publicado: Sciendo 2018
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Acceso en línea:https://doaj.org/article/4da84cb2aa1b4364b1331f238d2f3ac7
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spelling oai:doaj.org-article:4da84cb2aa1b4364b1331f238d2f3ac72021-12-02T14:59:04ZTrace Elements and Vitamin D in Gestational Diabetes0324-175010.2478/amb-2018-0009https://doaj.org/article/4da84cb2aa1b4364b1331f238d2f3ac72018-03-01T00:00:00Zhttps://doi.org/10.2478/amb-2018-0009https://doaj.org/toc/0324-1750Gestational diabetes mellitus (GDM), one of the most common pregnancy complications, is defined as glucose intolerance with onset or first recognition during pregnancy. Its prevalence varies worldwide in dependence on characteristics of the underlying population and applied diagnostic criteria. The etiology is multifactorial and not sufficiently elucidated. Available evidence suggests that the base of pathogenesis is relatively diminished insulin secretion coupled with pregnancy-induced insulin resistance. Modifiable and non-modifiable risk factors for development have been identified. Trace elements and vitamin D could be contributed to modifiable factors for prediction the risk in a large population. Essential trace elements in pregnancy are necessary to overcome systemic oxidative, metabolic and inflammatory stress. Evidence, still inconclusive, has been accumulated about the relation between higher incidence of vitamin D failure/deficiency during pregnancy and GDM. The lower level of 25-OH vitamin D could be associated with increased risk for anemia development, also including pregnant women. This review intends to provide an overview of the possible link between both vitamin D and trace elements as risk factors for GDM development.Genova MarianaAtanasova B.Ivanova I.Todorova K.Svinarov D.Sciendoarticlegestational diabetesmicroelementsvitamin d statusMedicineRENActa Medica Bulgarica, Vol 45, Iss 1, Pp 45-49 (2018)
institution DOAJ
collection DOAJ
language EN
topic gestational diabetes
microelements
vitamin d status
Medicine
R
spellingShingle gestational diabetes
microelements
vitamin d status
Medicine
R
Genova Mariana
Atanasova B.
Ivanova I.
Todorova K.
Svinarov D.
Trace Elements and Vitamin D in Gestational Diabetes
description Gestational diabetes mellitus (GDM), one of the most common pregnancy complications, is defined as glucose intolerance with onset or first recognition during pregnancy. Its prevalence varies worldwide in dependence on characteristics of the underlying population and applied diagnostic criteria. The etiology is multifactorial and not sufficiently elucidated. Available evidence suggests that the base of pathogenesis is relatively diminished insulin secretion coupled with pregnancy-induced insulin resistance. Modifiable and non-modifiable risk factors for development have been identified. Trace elements and vitamin D could be contributed to modifiable factors for prediction the risk in a large population. Essential trace elements in pregnancy are necessary to overcome systemic oxidative, metabolic and inflammatory stress. Evidence, still inconclusive, has been accumulated about the relation between higher incidence of vitamin D failure/deficiency during pregnancy and GDM. The lower level of 25-OH vitamin D could be associated with increased risk for anemia development, also including pregnant women. This review intends to provide an overview of the possible link between both vitamin D and trace elements as risk factors for GDM development.
format article
author Genova Mariana
Atanasova B.
Ivanova I.
Todorova K.
Svinarov D.
author_facet Genova Mariana
Atanasova B.
Ivanova I.
Todorova K.
Svinarov D.
author_sort Genova Mariana
title Trace Elements and Vitamin D in Gestational Diabetes
title_short Trace Elements and Vitamin D in Gestational Diabetes
title_full Trace Elements and Vitamin D in Gestational Diabetes
title_fullStr Trace Elements and Vitamin D in Gestational Diabetes
title_full_unstemmed Trace Elements and Vitamin D in Gestational Diabetes
title_sort trace elements and vitamin d in gestational diabetes
publisher Sciendo
publishDate 2018
url https://doaj.org/article/4da84cb2aa1b4364b1331f238d2f3ac7
work_keys_str_mv AT genovamariana traceelementsandvitamindingestationaldiabetes
AT atanasovab traceelementsandvitamindingestationaldiabetes
AT ivanovai traceelementsandvitamindingestationaldiabetes
AT todorovak traceelementsandvitamindingestationaldiabetes
AT svinarovd traceelementsandvitamindingestationaldiabetes
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