Role of serotonergic dorsal raphe neurons in hypercapnia-induced arousals

Dorsal raphe 5HT(DRSert) neurons regulate arousal from hypercapnia by their projections to the neurons in the external lateral parabrachial nucleus (PBel) that are glutamatergic and also express calcitonin gene related peptide (PBelCGRP). The DRSert input to the PBel modulates the arousal system to...

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Autores principales:	Satvinder Kaur, Roberto De Luca, Mudasir A. Khanday, Sathyajit S. Bandaru, Renner C. Thomas, Rebecca Y. Broadhurst, Anne Venner, William D. Todd, Patrick M. Fuller, Elda Arrigoni, Clifford B. Saper
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4da98725889140b2a381fff261262dfb
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spelling	oai:doaj.org-article:4da98725889140b2a381fff261262dfb2021-12-02T18:24:49ZRole of serotonergic dorsal raphe neurons in hypercapnia-induced arousals10.1038/s41467-020-16518-92041-1723https://doaj.org/article/4da98725889140b2a381fff261262dfb2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16518-9https://doaj.org/toc/2041-1723Dorsal raphe 5HT(DRSert) neurons regulate arousal from hypercapnia by their projections to the neurons in the external lateral parabrachial nucleus (PBel) that are glutamatergic and also express calcitonin gene related peptide (PBelCGRP). The DRSert input to the PBel modulates the arousal system to rising levels of blood CO2, and may be mediated by 5HT2a receptors on the PBelCGRP neurons.Satvinder KaurRoberto De LucaMudasir A. KhandaySathyajit S. BandaruRenner C. ThomasRebecca Y. BroadhurstAnne VennerWilliam D. ToddPatrick M. FullerElda ArrigoniClifford B. SaperNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Satvinder Kaur Roberto De Luca Mudasir A. Khanday Sathyajit S. Bandaru Renner C. Thomas Rebecca Y. Broadhurst Anne Venner William D. Todd Patrick M. Fuller Elda Arrigoni Clifford B. Saper Role of serotonergic dorsal raphe neurons in hypercapnia-induced arousals
description	Dorsal raphe 5HT(DRSert) neurons regulate arousal from hypercapnia by their projections to the neurons in the external lateral parabrachial nucleus (PBel) that are glutamatergic and also express calcitonin gene related peptide (PBelCGRP). The DRSert input to the PBel modulates the arousal system to rising levels of blood CO2, and may be mediated by 5HT2a receptors on the PBelCGRP neurons.
format	article
author	Satvinder Kaur Roberto De Luca Mudasir A. Khanday Sathyajit S. Bandaru Renner C. Thomas Rebecca Y. Broadhurst Anne Venner William D. Todd Patrick M. Fuller Elda Arrigoni Clifford B. Saper
author_facet	Satvinder Kaur Roberto De Luca Mudasir A. Khanday Sathyajit S. Bandaru Renner C. Thomas Rebecca Y. Broadhurst Anne Venner William D. Todd Patrick M. Fuller Elda Arrigoni Clifford B. Saper
author_sort	Satvinder Kaur
title	Role of serotonergic dorsal raphe neurons in hypercapnia-induced arousals
title_short	Role of serotonergic dorsal raphe neurons in hypercapnia-induced arousals
title_full	Role of serotonergic dorsal raphe neurons in hypercapnia-induced arousals
title_fullStr	Role of serotonergic dorsal raphe neurons in hypercapnia-induced arousals
title_full_unstemmed	Role of serotonergic dorsal raphe neurons in hypercapnia-induced arousals
title_sort	role of serotonergic dorsal raphe neurons in hypercapnia-induced arousals
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/4da98725889140b2a381fff261262dfb
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Role of serotonergic dorsal raphe neurons in hypercapnia-induced arousals

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