Assessment of corneal substrate biomechanics and its effect on epithelial stem cell maintenance and differentiation
The link between how the stiffness of the cornea affects stem cells is unclear. Here, the authors use Brillouin spectro-microscopy to show that mechanical properties of the cornea affect epithelial stem cells and after injury, treating the cornea with collagenase suppresses YAP activation, assisting...
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| Autores principales: | , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2019
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/4db489443ac3438cb327cb65509749c4 |
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| Sumario: | The link between how the stiffness of the cornea affects stem cells is unclear. Here, the authors use Brillouin spectro-microscopy to show that mechanical properties of the cornea affect epithelial stem cells and after injury, treating the cornea with collagenase suppresses YAP activation, assisting in regeneration. |
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