Nanotheranostics – a review of recent publications

Li-Sheng Wang, Min-Chieh Chuang, Ja-an Annie HoDepartment of Biochemical Science and Technology, National Taiwan University, Taipei, TaiwanAbstract: Theranostics is referred to as a treatment strategy that combines therapeutics with diagnostics, aiming to monitor the response to treatment and increa...

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Autores principales: Wang LS, Chuang MC, Ho JA
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Publicado: Dove Medical Press 2012
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Acceso en línea:https://doaj.org/article/4dc06a89e2334973a9e6ef594f59cca7
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spelling oai:doaj.org-article:4dc06a89e2334973a9e6ef594f59cca72021-12-02T00:31:18ZNanotheranostics – a review of recent publications1176-91141178-2013https://doaj.org/article/4dc06a89e2334973a9e6ef594f59cca72012-08-01T00:00:00Zhttp://www.dovepress.com/nanotheranostics-ndash-a-review-of-recent-publications-a10796https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013Li-Sheng Wang, Min-Chieh Chuang, Ja-an Annie HoDepartment of Biochemical Science and Technology, National Taiwan University, Taipei, TaiwanAbstract: Theranostics is referred to as a treatment strategy that combines therapeutics with diagnostics, aiming to monitor the response to treatment and increase drug efficacy and safety, which would be a key part of personalized medicine and require considerable advances in predictive medicine. Theranostics associates with both a diagnosis that tests patients for possible reactions to taking new medication and targeted drug delivery based on the test results. Emerging nanotechnology provides a great deal of opportunity to design and develop such combination agents, permitting the delivery of therapeutics and concurrently allowing the detection modality to be used not only before or after but also throughout the entire treatment regimen. The introduction of nanotheranostics into routine health care has still a long way to go, since evaluations on cytotoxicity, genotoxicity, and immunotoxicity of prospective nanotheranostics, demonstration of cost-effectiveness, and availability of appropriate accessible testing systems are still required. An extensive review, from a chemistry point of view, of the recent development of nanotheranostics and its in vitro and in vivo applications are herein presented.Keywords: theranostics, therapeutics, diagnostics, nanomaterialWang LSChuang MCHo JADove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2012, Iss default, Pp 4679-4695 (2012)
institution DOAJ
collection DOAJ
language EN
topic Medicine (General)
R5-920
spellingShingle Medicine (General)
R5-920
Wang LS
Chuang MC
Ho JA
Nanotheranostics – a review of recent publications
description Li-Sheng Wang, Min-Chieh Chuang, Ja-an Annie HoDepartment of Biochemical Science and Technology, National Taiwan University, Taipei, TaiwanAbstract: Theranostics is referred to as a treatment strategy that combines therapeutics with diagnostics, aiming to monitor the response to treatment and increase drug efficacy and safety, which would be a key part of personalized medicine and require considerable advances in predictive medicine. Theranostics associates with both a diagnosis that tests patients for possible reactions to taking new medication and targeted drug delivery based on the test results. Emerging nanotechnology provides a great deal of opportunity to design and develop such combination agents, permitting the delivery of therapeutics and concurrently allowing the detection modality to be used not only before or after but also throughout the entire treatment regimen. The introduction of nanotheranostics into routine health care has still a long way to go, since evaluations on cytotoxicity, genotoxicity, and immunotoxicity of prospective nanotheranostics, demonstration of cost-effectiveness, and availability of appropriate accessible testing systems are still required. An extensive review, from a chemistry point of view, of the recent development of nanotheranostics and its in vitro and in vivo applications are herein presented.Keywords: theranostics, therapeutics, diagnostics, nanomaterial
format article
author Wang LS
Chuang MC
Ho JA
author_facet Wang LS
Chuang MC
Ho JA
author_sort Wang LS
title Nanotheranostics – a review of recent publications
title_short Nanotheranostics – a review of recent publications
title_full Nanotheranostics – a review of recent publications
title_fullStr Nanotheranostics – a review of recent publications
title_full_unstemmed Nanotheranostics – a review of recent publications
title_sort nanotheranostics – a review of recent publications
publisher Dove Medical Press
publishDate 2012
url https://doaj.org/article/4dc06a89e2334973a9e6ef594f59cca7
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