Essential factors for incompatible DNA end joining at chromosomal DNA double strand breaks in vivo.
Non-homologous end joining (NHEJ) is a major pathway for the repair of DNA double strand break (DSBs) with incompatible DNA ends, which are often generated by ionizing irradiation. In vitro reconstitution studies have indicated that NHEJ of incompatible DNA ends requires not only the core steps of s...
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Autores principales: | Hideaki Ogiwara, Takashi Kohno |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/4dc41e656cee4a579a156e96079d595d |
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