EFFICACY OF SALBUTAMOL DELIVERED THROUGH A METERED DOSE INHALER & SPACER IN CHILDREN WITH ACUTE EXACERBATION OF ASTHMA

Objective: To assess efficacy of salbutamol delivered through metered dose inhaler (MDI) - spacer in paediatric patients with acute exacerbation of asthma. Study Design: Prospective observational study. Place and Duration of Study: Department of Paediatrics, Pakistan Naval Ship, Shifa Hospital...

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Autores principales:	Ali Mujtaba Tahir, Waqas Akhtar, Salah Ud Din Balooch, Waqas Ahmed, Ali Murtaza Samar, Amina Sohail
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2021
Materias:	asthma exacerbation clinical asthma score metered dose inhaler salbutamol spacer Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/4dc81f9631b84dc5a4292b800fda798c
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spelling	oai:doaj.org-article:4dc81f9631b84dc5a4292b800fda798c2021-12-02T16:32:52ZEFFICACY OF SALBUTAMOL DELIVERED THROUGH A METERED DOSE INHALER & SPACER IN CHILDREN WITH ACUTE EXACERBATION OF ASTHMA0030-96482411-884210.51253/pafmj.v71i2.4388https://doaj.org/article/4dc81f9631b84dc5a4292b800fda798c2021-04-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/4388https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To assess efficacy of salbutamol delivered through metered dose inhaler (MDI) - spacer in paediatric patients with acute exacerbation of asthma. Study Design: Prospective observational study. Place and Duration of Study: Department of Paediatrics, Pakistan Naval Ship, Shifa Hospital, Karachi-Pakistan, from Jan to Dec 2018. Methodology: Ninety Five patients aged ≥6 to ≤12 years, with acute asthma exacerbation were enrolled. Any patient with fever, clinical asthma score (CAS) >7, on home treatment with drugs delivered through nebulization or on oral steroids was excluded. Clinical asthma score recorded on presentation, followed with salbutamol via Metered Dose Inhaler & spacer at dose of 400 µgm (4 x puffs of 100 µgm). Clinical asthma score rechecked after 20 min. Response to salbutamol was then compared in relation to the presenting Clinical asthma score. Results: Out of 95 children, 45 (47.9%) were male & 50 (52.1%) female with 67.4% having positive family history for asthma. Average premedication clinical asthma score was 2.44. Sixty nine (72.9%) patients had an adequate response as they exhibited clinical asthma score of 0 or fall in score of ≥2. Patients with adequate response had average clinical asthma score of 2.07 on presentation in contrast to 3.42 with inadequate response. Conclusion: Salbutamol delivered via Metered Dose Inhaler & spacer at dose of 400 µgm is an effective medication for quick relief in children with acute exacerbation of asthma. Moreover, its administration at a point where exacerbation is not much severe steers us towards more favourable outcome.Ali Mujtaba TahirWaqas AkhtarSalah Ud Din BaloochWaqas AhmedAli Murtaza SamarAmina SohailArmy Medical College Rawalpindiarticleasthma exacerbationclinical asthma scoremetered dose inhalersalbutamolspacerMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 71, Iss 2, Pp 438-41 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	asthma exacerbation clinical asthma score metered dose inhaler salbutamol spacer Medicine R Medicine (General) R5-920
spellingShingle	asthma exacerbation clinical asthma score metered dose inhaler salbutamol spacer Medicine R Medicine (General) R5-920 Ali Mujtaba Tahir Waqas Akhtar Salah Ud Din Balooch Waqas Ahmed Ali Murtaza Samar Amina Sohail EFFICACY OF SALBUTAMOL DELIVERED THROUGH A METERED DOSE INHALER & SPACER IN CHILDREN WITH ACUTE EXACERBATION OF ASTHMA
description	Objective: To assess efficacy of salbutamol delivered through metered dose inhaler (MDI) - spacer in paediatric patients with acute exacerbation of asthma. Study Design: Prospective observational study. Place and Duration of Study: Department of Paediatrics, Pakistan Naval Ship, Shifa Hospital, Karachi-Pakistan, from Jan to Dec 2018. Methodology: Ninety Five patients aged ≥6 to ≤12 years, with acute asthma exacerbation were enrolled. Any patient with fever, clinical asthma score (CAS) >7, on home treatment with drugs delivered through nebulization or on oral steroids was excluded. Clinical asthma score recorded on presentation, followed with salbutamol via Metered Dose Inhaler & spacer at dose of 400 µgm (4 x puffs of 100 µgm). Clinical asthma score rechecked after 20 min. Response to salbutamol was then compared in relation to the presenting Clinical asthma score. Results: Out of 95 children, 45 (47.9%) were male & 50 (52.1%) female with 67.4% having positive family history for asthma. Average premedication clinical asthma score was 2.44. Sixty nine (72.9%) patients had an adequate response as they exhibited clinical asthma score of 0 or fall in score of ≥2. Patients with adequate response had average clinical asthma score of 2.07 on presentation in contrast to 3.42 with inadequate response. Conclusion: Salbutamol delivered via Metered Dose Inhaler & spacer at dose of 400 µgm is an effective medication for quick relief in children with acute exacerbation of asthma. Moreover, its administration at a point where exacerbation is not much severe steers us towards more favourable outcome.
format	article
author	Ali Mujtaba Tahir Waqas Akhtar Salah Ud Din Balooch Waqas Ahmed Ali Murtaza Samar Amina Sohail
author_facet	Ali Mujtaba Tahir Waqas Akhtar Salah Ud Din Balooch Waqas Ahmed Ali Murtaza Samar Amina Sohail
author_sort	Ali Mujtaba Tahir
title	EFFICACY OF SALBUTAMOL DELIVERED THROUGH A METERED DOSE INHALER & SPACER IN CHILDREN WITH ACUTE EXACERBATION OF ASTHMA
title_short	EFFICACY OF SALBUTAMOL DELIVERED THROUGH A METERED DOSE INHALER & SPACER IN CHILDREN WITH ACUTE EXACERBATION OF ASTHMA
title_full	EFFICACY OF SALBUTAMOL DELIVERED THROUGH A METERED DOSE INHALER & SPACER IN CHILDREN WITH ACUTE EXACERBATION OF ASTHMA
title_fullStr	EFFICACY OF SALBUTAMOL DELIVERED THROUGH A METERED DOSE INHALER & SPACER IN CHILDREN WITH ACUTE EXACERBATION OF ASTHMA
title_full_unstemmed	EFFICACY OF SALBUTAMOL DELIVERED THROUGH A METERED DOSE INHALER & SPACER IN CHILDREN WITH ACUTE EXACERBATION OF ASTHMA
title_sort	efficacy of salbutamol delivered through a metered dose inhaler & spacer in children with acute exacerbation of asthma
publisher	Army Medical College Rawalpindi
publishDate	2021
url	https://doaj.org/article/4dc81f9631b84dc5a4292b800fda798c
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EFFICACY OF SALBUTAMOL DELIVERED THROUGH A METERED DOSE INHALER & SPACER IN CHILDREN WITH ACUTE EXACERBATION OF ASTHMA

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