Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus

Decline of brain function during aging is associated with epigenetic changes, including DNA methylation. Here the authors provide evidence that environmental enrichment delays age-related DNA methylation alterations in the mouse hippocampus.

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Detalles Bibliográficos
Autores principales: Sara Zocher, Rupert W. Overall, Mathias Lesche, Andreas Dahl, Gerd Kempermann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4dcdcefab939400595faeed6bc18e70f
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Sumario:Decline of brain function during aging is associated with epigenetic changes, including DNA methylation. Here the authors provide evidence that environmental enrichment delays age-related DNA methylation alterations in the mouse hippocampus.