Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus

Decline of brain function during aging is associated with epigenetic changes, including DNA methylation. Here the authors provide evidence that environmental enrichment delays age-related DNA methylation alterations in the mouse hippocampus.

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Autores principales:	Sara Zocher, Rupert W. Overall, Mathias Lesche, Andreas Dahl, Gerd Kempermann
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4dcdcefab939400595faeed6bc18e70f
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spelling	oai:doaj.org-article:4dcdcefab939400595faeed6bc18e70f2021-12-02T17:44:52ZEnvironmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus10.1038/s41467-021-23993-12041-1723https://doaj.org/article/4dcdcefab939400595faeed6bc18e70f2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23993-1https://doaj.org/toc/2041-1723Decline of brain function during aging is associated with epigenetic changes, including DNA methylation. Here the authors provide evidence that environmental enrichment delays age-related DNA methylation alterations in the mouse hippocampus.Sara ZocherRupert W. OverallMathias LescheAndreas DahlGerd KempermannNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sara Zocher Rupert W. Overall Mathias Lesche Andreas Dahl Gerd Kempermann Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus
description	Decline of brain function during aging is associated with epigenetic changes, including DNA methylation. Here the authors provide evidence that environmental enrichment delays age-related DNA methylation alterations in the mouse hippocampus.
format	article
author	Sara Zocher Rupert W. Overall Mathias Lesche Andreas Dahl Gerd Kempermann
author_facet	Sara Zocher Rupert W. Overall Mathias Lesche Andreas Dahl Gerd Kempermann
author_sort	Sara Zocher
title	Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus
title_short	Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus
title_full	Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus
title_fullStr	Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus
title_full_unstemmed	Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus
title_sort	environmental enrichment preserves a young dna methylation landscape in the aged mouse hippocampus
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4dcdcefab939400595faeed6bc18e70f
work_keys_str_mv	AT sarazocher environmentalenrichmentpreservesayoungdnamethylationlandscapeintheagedmousehippocampus AT rupertwoverall environmentalenrichmentpreservesayoungdnamethylationlandscapeintheagedmousehippocampus AT mathiaslesche environmentalenrichmentpreservesayoungdnamethylationlandscapeintheagedmousehippocampus AT andreasdahl environmentalenrichmentpreservesayoungdnamethylationlandscapeintheagedmousehippocampus AT gerdkempermann environmentalenrichmentpreservesayoungdnamethylationlandscapeintheagedmousehippocampus
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Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus

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