Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement

Plasmacytoid dendritic cells produce type I interferons in response to viral sensing. Here the authors show that amines inhibit these plasmacytoid dendritic cell responses through CXCR4 engagement.

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Autores principales: Nikaïa Smith, Nicolas Pietrancosta, Sophia Davidson, Jacques Dutrieux, Lise Chauveau, Pasquale Cutolo, Michel Dy, Daniel Scott-Algara, Bénédicte Manoury, Onofrio Zirafi, Isabelle McCort-Tranchepain, Thierry Durroux, Françoise Bachelerie, Olivier Schwartz, Jan Münch, Andreas Wack, Sébastien Nisole, Jean-Philippe Herbeuval
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Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/4dcfeb35184e41db9075187f20ab2655
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spelling oai:doaj.org-article:4dcfeb35184e41db9075187f20ab26552021-12-02T14:42:35ZNatural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement10.1038/ncomms142532041-1723https://doaj.org/article/4dcfeb35184e41db9075187f20ab26552017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14253https://doaj.org/toc/2041-1723Plasmacytoid dendritic cells produce type I interferons in response to viral sensing. Here the authors show that amines inhibit these plasmacytoid dendritic cell responses through CXCR4 engagement.Nikaïa SmithNicolas PietrancostaSophia DavidsonJacques DutrieuxLise ChauveauPasquale CutoloMichel DyDaniel Scott-AlgaraBénédicte ManouryOnofrio ZirafiIsabelle McCort-TranchepainThierry DurrouxFrançoise BachelerieOlivier SchwartzJan MünchAndreas WackSébastien NisoleJean-Philippe HerbeuvalNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Nikaïa Smith
Nicolas Pietrancosta
Sophia Davidson
Jacques Dutrieux
Lise Chauveau
Pasquale Cutolo
Michel Dy
Daniel Scott-Algara
Bénédicte Manoury
Onofrio Zirafi
Isabelle McCort-Tranchepain
Thierry Durroux
Françoise Bachelerie
Olivier Schwartz
Jan Münch
Andreas Wack
Sébastien Nisole
Jean-Philippe Herbeuval
Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement
description Plasmacytoid dendritic cells produce type I interferons in response to viral sensing. Here the authors show that amines inhibit these plasmacytoid dendritic cell responses through CXCR4 engagement.
format article
author Nikaïa Smith
Nicolas Pietrancosta
Sophia Davidson
Jacques Dutrieux
Lise Chauveau
Pasquale Cutolo
Michel Dy
Daniel Scott-Algara
Bénédicte Manoury
Onofrio Zirafi
Isabelle McCort-Tranchepain
Thierry Durroux
Françoise Bachelerie
Olivier Schwartz
Jan Münch
Andreas Wack
Sébastien Nisole
Jean-Philippe Herbeuval
author_facet Nikaïa Smith
Nicolas Pietrancosta
Sophia Davidson
Jacques Dutrieux
Lise Chauveau
Pasquale Cutolo
Michel Dy
Daniel Scott-Algara
Bénédicte Manoury
Onofrio Zirafi
Isabelle McCort-Tranchepain
Thierry Durroux
Françoise Bachelerie
Olivier Schwartz
Jan Münch
Andreas Wack
Sébastien Nisole
Jean-Philippe Herbeuval
author_sort Nikaïa Smith
title Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement
title_short Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement
title_full Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement
title_fullStr Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement
title_full_unstemmed Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement
title_sort natural amines inhibit activation of human plasmacytoid dendritic cells through cxcr4 engagement
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/4dcfeb35184e41db9075187f20ab2655
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