In Vitro and In Vivo Characterization of PCC0104005, a Novel Modulator of Serotonin-Dopamine Activity, as an Atypical Antipsychotic Drug
Abstract PCC0104005 is a novel drug candidate for treating schizophrenia that displays high affinity for serotonin, dopamine, and noradrenaline receptors, including partial agonism at dopamine D2, D3, D4, serotonin 5-HT1A, and 5-HT2A receptors and antagonism at 5-HT2B, 5-HT6, and 5-HT7 receptors. PC...
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Autores principales: | , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2018
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Acceso en línea: | https://doaj.org/article/4dd4ec75184b4e43802e26ea64c93dea |
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