A cell cycle kinase with tandem sensory PAS domains integrates cell fate cues

The membrane-bound kinase CckA controls the activity of the Caulobacter crescentusmaster regulator CtrA, which in turn coordinates asymmetric cell division. Here, the authors show that CckA contains two sensory domains that have distinct sensitivities to fluctuations in cyclic-di-GMP concentration a...

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Autores principales:	Thomas H. Mann, W. Seth Childers, Jimmy A. Blair, Michael R. Eckart, Lucy Shapiro
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4dd75cb85cdd42dfa5b4a8cc1ccac2ef
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id	oai:doaj.org-article:4dd75cb85cdd42dfa5b4a8cc1ccac2ef
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spelling	oai:doaj.org-article:4dd75cb85cdd42dfa5b4a8cc1ccac2ef2021-12-02T15:34:08ZA cell cycle kinase with tandem sensory PAS domains integrates cell fate cues10.1038/ncomms114542041-1723https://doaj.org/article/4dd75cb85cdd42dfa5b4a8cc1ccac2ef2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11454https://doaj.org/toc/2041-1723The membrane-bound kinase CckA controls the activity of the Caulobacter crescentusmaster regulator CtrA, which in turn coordinates asymmetric cell division. Here, the authors show that CckA contains two sensory domains that have distinct sensitivities to fluctuations in cyclic-di-GMP concentration and subcellular niche.Thomas H. MannW. Seth ChildersJimmy A. BlairMichael R. EckartLucy ShapiroNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Thomas H. Mann W. Seth Childers Jimmy A. Blair Michael R. Eckart Lucy Shapiro A cell cycle kinase with tandem sensory PAS domains integrates cell fate cues
description	The membrane-bound kinase CckA controls the activity of the Caulobacter crescentusmaster regulator CtrA, which in turn coordinates asymmetric cell division. Here, the authors show that CckA contains two sensory domains that have distinct sensitivities to fluctuations in cyclic-di-GMP concentration and subcellular niche.
format	article
author	Thomas H. Mann W. Seth Childers Jimmy A. Blair Michael R. Eckart Lucy Shapiro
author_facet	Thomas H. Mann W. Seth Childers Jimmy A. Blair Michael R. Eckart Lucy Shapiro
author_sort	Thomas H. Mann
title	A cell cycle kinase with tandem sensory PAS domains integrates cell fate cues
title_short	A cell cycle kinase with tandem sensory PAS domains integrates cell fate cues
title_full	A cell cycle kinase with tandem sensory PAS domains integrates cell fate cues
title_fullStr	A cell cycle kinase with tandem sensory PAS domains integrates cell fate cues
title_full_unstemmed	A cell cycle kinase with tandem sensory PAS domains integrates cell fate cues
title_sort	cell cycle kinase with tandem sensory pas domains integrates cell fate cues
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/4dd75cb85cdd42dfa5b4a8cc1ccac2ef
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A cell cycle kinase with tandem sensory PAS domains integrates cell fate cues

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