Interrogating the degradation pathways of unstable mRNAs with XRN1-resistant sequences
Degradation of messenger RNA is a key regulatory step in controlling eukaryotic gene expression. Here the authors present xrFrag, a molecular tool to interrogate the extent and directionality of mRNA turnover by the detection of stabilized decay intermediates produced by several common decay pathway...
Guardado en:
Autores principales: | Volker Boehm, Jennifer V. Gerbracht, Marie-Charlotte Marx, Niels H. Gehring |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
|
Materias: | |
Acceso en línea: | https://doaj.org/article/4df3f5547cd041fa9a60258e7949e822 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins
por: Bernat Blasco-Moreno, et al.
Publicado: (2019) -
Sequence features of E. coli mRNAs affect their degradation.
por: Gal Lenz, et al.
Publicado: (2011) -
High-Throughput Sequencing Profiles About lncRNAs and mRNAs of Ovarian Granulosa Cells in Polycystic Ovary Syndrome
por: Yanjun Zheng, et al.
Publicado: (2021) -
Pseudoknot length modulates the folding, conformational dynamics, and robustness of Xrn1 resistance of flaviviral xrRNAs
por: Xiaolin Niu, et al.
Publicado: (2021) -
Pumilio-dependent localization of mRNAs at the cell front coordinates multiple pathways required for chemotaxis
por: Manuel Hotz, et al.
Publicado: (2017)