Derivation and Validation of Genome‐Wide Polygenic Score for Ischemic Heart Failure

Derivation and Validation of Genome‐Wide Polygenic Score for Ischemic Heart Failure

Background Despite advances in cardiovascular disease and risk factor management, mortality from ischemic heart failure (HF) in patients with coronary artery disease (CAD) remains high. Given the partial role of genetics in HF and lack of reliable risk stratification tools, we developed and validate...

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Auteurs principaux: Ishan Paranjpe, Noah L. Tsao, Jessica K. De Freitas, Renae Judy, Kumardeep Chaudhary, Iain S. Forrest, Suraj K. Jaladanki, Manish Paranjpe, Pranav Sharma, Benjamin S. Glicksberg, Jagat Narula, Ron Do, Scott M. Damrauer, Girish N. Nadkarni
Format: article
Langue:EN
Publié: Wiley 2021
Sujets:
genomics
heart failure
personalized medicine
polygenic risk score
Diseases of the circulatory (Cardiovascular) system
RC666-701
Accès en ligne:https://doaj.org/article/4df61ee4967e4e3c85259d214fe1e2ac
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https://doaj.org/article/4df61ee4967e4e3c85259d214fe1e2ac

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