TGFβ-activation by dendritic cells drives Th17 induction and intestinal contractility and augments the expulsion of the parasite Trichinella spiralis in mice.
Helminths are highly prevalent metazoan parasites that infect over a billion of the world's population. Hosts have evolved numerous mechanisms to drive the expulsion of these parasites via Th2-driven immunity, but these responses must be tightly controlled to prevent equally devastating immunop...
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Autores principales: | Nicola Steel, Aduragbemi A Faniyi, Sayema Rahman, Stefanie Swietlik, Beata I Czajkowska, Bethany T Chan, Alexander Hardgrave, Anthony Steel, Tim D Sparwasser, Mushref B Assas, Richard K Grencis, Mark A Travis, John J Worthington |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/4df84396880e471badbb38cffcabcad0 |
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