Silencing Nfix rescues muscular dystrophy by delaying muscle regeneration

Strategies aimed at promoting muscle regeneration to treat muscular dystrophy have met with limited success. Here the authors show instead that delaying muscle regeneration, by ablation of the transcription factor Nfix, ameliorates muscular dystrophy in mice.

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Autores principales:	Giuliana Rossi, Chiara Bonfanti, Stefania Antonini, Mattia Bastoni, Stefania Monteverde, Anna Innocenzi, Marielle Saclier, Valentina Taglietti, Graziella Messina
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4dfcc452d0b14567b01bb5bcd9666918
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spelling	oai:doaj.org-article:4dfcc452d0b14567b01bb5bcd96669182021-12-02T15:39:04ZSilencing Nfix rescues muscular dystrophy by delaying muscle regeneration10.1038/s41467-017-01098-y2041-1723https://doaj.org/article/4dfcc452d0b14567b01bb5bcd96669182017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01098-yhttps://doaj.org/toc/2041-1723Strategies aimed at promoting muscle regeneration to treat muscular dystrophy have met with limited success. Here the authors show instead that delaying muscle regeneration, by ablation of the transcription factor Nfix, ameliorates muscular dystrophy in mice.Giuliana RossiChiara BonfantiStefania AntoniniMattia BastoniStefania MonteverdeAnna InnocenziMarielle SaclierValentina TagliettiGraziella MessinaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Giuliana Rossi Chiara Bonfanti Stefania Antonini Mattia Bastoni Stefania Monteverde Anna Innocenzi Marielle Saclier Valentina Taglietti Graziella Messina Silencing Nfix rescues muscular dystrophy by delaying muscle regeneration
description	Strategies aimed at promoting muscle regeneration to treat muscular dystrophy have met with limited success. Here the authors show instead that delaying muscle regeneration, by ablation of the transcription factor Nfix, ameliorates muscular dystrophy in mice.
format	article
author	Giuliana Rossi Chiara Bonfanti Stefania Antonini Mattia Bastoni Stefania Monteverde Anna Innocenzi Marielle Saclier Valentina Taglietti Graziella Messina
author_facet	Giuliana Rossi Chiara Bonfanti Stefania Antonini Mattia Bastoni Stefania Monteverde Anna Innocenzi Marielle Saclier Valentina Taglietti Graziella Messina
author_sort	Giuliana Rossi
title	Silencing Nfix rescues muscular dystrophy by delaying muscle regeneration
title_short	Silencing Nfix rescues muscular dystrophy by delaying muscle regeneration
title_full	Silencing Nfix rescues muscular dystrophy by delaying muscle regeneration
title_fullStr	Silencing Nfix rescues muscular dystrophy by delaying muscle regeneration
title_full_unstemmed	Silencing Nfix rescues muscular dystrophy by delaying muscle regeneration
title_sort	silencing nfix rescues muscular dystrophy by delaying muscle regeneration
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/4dfcc452d0b14567b01bb5bcd9666918
work_keys_str_mv	AT giulianarossi silencingnfixrescuesmusculardystrophybydelayingmuscleregeneration AT chiarabonfanti silencingnfixrescuesmusculardystrophybydelayingmuscleregeneration AT stefaniaantonini silencingnfixrescuesmusculardystrophybydelayingmuscleregeneration AT mattiabastoni silencingnfixrescuesmusculardystrophybydelayingmuscleregeneration AT stefaniamonteverde silencingnfixrescuesmusculardystrophybydelayingmuscleregeneration AT annainnocenzi silencingnfixrescuesmusculardystrophybydelayingmuscleregeneration AT mariellesaclier silencingnfixrescuesmusculardystrophybydelayingmuscleregeneration AT valentinataglietti silencingnfixrescuesmusculardystrophybydelayingmuscleregeneration AT graziellamessina silencingnfixrescuesmusculardystrophybydelayingmuscleregeneration
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Silencing Nfix rescues muscular dystrophy by delaying muscle regeneration

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