Phage Resistance in Multidrug-Resistant <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> ST258 Evolves via Diverse Mutations That Culminate in Impaired Adsorption
ABSTRACT The evolution of phage resistance poses an inevitable threat to the efficacy of phage therapy. The strategic selection of phage combinations that impose high genetic barriers to resistance and/or high compensatory fitness costs may mitigate this threat. However, for such a strategy to be ef...
Guardado en:
Autores principales: | Shayla Hesse, Manoj Rajaure, Erin Wall, Joy Johnson, Valery Bliskovsky, Susan Gottesman, Sankar Adhya |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/4e041000c950464486454e9b28544844 |
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